FAM25G Inhibitors
The chemical class of FAM25G Inhibitors encompasses a variety of compounds that can potentially inhibit the activity of the FAM25G protein, either directly or indirectly. FAM25G may be involved in various signaling pathways crucial for cell growth, proliferation, and survival, including those mediated by phosphoinositide 3-kinases (PI3Ks), extracellular signal-regulated kinase (ERK), mammalian target of rapamycin (mTOR), and p38 mitogen-activated protein kinase (MAPK). Direct inhibitors targeting these pathways, such as LY294002 for PI3Ks, U0126 for MEK, rapamycin for mTOR, and SB203580 for p38 MAPK, can disrupt the downstream signaling events involving FAM25G, thereby inhibiting its function.
Indirect inhibitors, such as Wortmannin, PD98059, and Torin 1, target key components upstream of these signaling pathways, leading to downstream effects that interfere with FAM25G-mediated cellular processes. These compounds act by blocking the activity of enzymes or kinases crucial for the activation of signaling cascades involving FAM25G. Additionally, structural analogs of known inhibitors, like LY303511 for LY294002 and AZD8055 for rapamycin, offer alternative options for inhibiting the same targets, potentially providing versatility in experimental settings. Overall, the diverse array of inhibitors targeting various signaling pathways associated with FAM25G highlights the importance of this protein in cellular physiology and offers valuable tools for investigating its biological functions.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a potent inhibitor of phosphoinositide 3-kinases (PI3Ks), which are involved in various cellular processes including cell growth, proliferation, and survival. FAM25G may be associated with PI3K-mediated signaling pathways, and inhibition of PI3K activity by LY294002 can potentially disrupt these pathways, leading to inhibition of FAM25G function. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a selective inhibitor of mitogen-activated protein kinase kinase (MEK), a key component of the extracellular signal-regulated kinase (ERK) signaling pathway. FAM25G may be involved in ERK-mediated signaling cascades, and inhibition of MEK by U0126 can disrupt ERK activation, potentially inhibiting FAM25G activity indirectly. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an inhibitor of the mammalian target of rapamycin (mTOR), a serine/threonine kinase involved in the regulation of cell growth, proliferation, and metabolism. FAM25G may be regulated by mTOR signaling pathways, and inhibition of mTOR by rapamycin can potentially disrupt these pathways, leading to inhibition of FAM25G function. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a selective inhibitor of p38 mitogen-activated protein kinase (MAPK), which plays a role in various cellular processes including inflammation and stress response. FAM25G may be associated with p38 MAPK signaling pathways, and inhibition of p38 MAPK by SB203580 can potentially disrupt these pathways, leading to inhibition of FAM25G function indirectly. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent inhibitor of phosphoinositide 3-kinases (PI3Ks), enzymes involved in various cellular processes including vesicle trafficking. FAM25G may be associated with PI3K-mediated signaling pathways, and inhibition of PI3K activity by wortmannin can potentially disrupt these pathways, leading to inhibition of FAM25G function indirectly. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a selective inhibitor of MEK1/2, which are upstream activators of the ERK signaling pathway. FAM25G may be involved in ERK-mediated signaling cascades, and inhibition of MEK by PD98059 can disrupt ERK activation, potentially inhibiting FAM25G activity indirectly. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $240.00 | 7 | |
Torin 1 is a potent inhibitor of the mammalian target of rapamycin (mTOR), a serine/threonine kinase involved in cell growth and survival pathways. FAM25G may be regulated by mTOR signaling pathways, and inhibition of mTOR by Torin 1 can potentially disrupt these pathways, leading to inhibition of FAM25G function indirectly. | ||||||
PD 169316 | 152121-53-4 | sc-204168 sc-204168A sc-204168B sc-204168C | 1 mg 5 mg 10 mg 25 mg | $86.00 $153.00 $275.00 $452.00 | 3 | |
SB202190 is a selective inhibitor of p38 mitogen-activated protein kinase (MAPK), which plays a role in various cellular processes including inflammation and stress response. FAM25G may be associated with p38 MAPK signaling pathways, and inhibition of p38 MAPK by SB202190 can potentially disrupt these pathways, leading to inhibition of FAM25G function indirectly. | ||||||
BKM120 | 944396-07-0 | sc-364437 sc-364437A sc-364437B sc-364437C | 5 mg 10 mg 25 mg 50 mg | $173.00 $230.00 $275.00 $332.00 | 9 | |
BKM120 is a potent inhibitor of phosphoinositide 3-kinases (PI3Ks), which are involved in various cellular processes including cell growth, proliferation, and survival. FAM25G may be associated with PI3K-mediated signaling pathways, and inhibition of PI3K activity by BKM120 can potentially disrupt these pathways, leading to inhibition of FAM25G function. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $160.00 $345.00 | 12 | |
AZD8055 is an ATP-competitive inhibitor of the mammalian target of rapamycin (mTOR), a serine/threonine kinase involved in cell growth and survival pathways. FAM25G may be regulated by mTOR signaling pathways, and inhibition of mTOR by AZD8055 can potentially disrupt these pathways, leading to inhibition of FAM25G function indirectly. | ||||||