FAM169A inhibitors target key signaling pathways associated with the gene. Wortmannin and LY294002 specifically inhibit PI3-kinase, a critical player in these pathways, disrupting FAM169A-associated functions. U0126 and PD98059 act by inhibiting MEK1/2, downstream of FAM169A, impacting signal transduction. SB203580 and SP600125 disrupt pathways by inhibiting p38 MAP kinase and JNK, respectively, both linked to FAM169A. Rapamycin inhibits mTOR, a central regulator in FAM169A-associated pathways. Staurosporine, Calphostin C, and Bay 11-7082 are broad inhibitors affecting multiple pathways, including those involving FAM169A. Additionally, exploring Wortmannin derivatives and PI-103 offers potential for enhanced specificity against PI3-kinase and mTOR, respectively, providing diverse options for modulating FAM169A-related cellular processes. These inhibitors collectively interfere with intracellular signaling cascades, highlighting their utility in studying FAM169A function and associated pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Derivatives of Wortmannin can be explored for enhanced specificity against PI3-kinase, affecting FAM169A pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a potent PI3-kinase inhibitor, preventing the activation of pathways involving FAM169A. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 inhibits MEK1/2, downstream of FAM169A-associated pathways, disrupting signaling cascades. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 targets p38 MAP kinase, influencing pathways related to FAM169A and potentially inhibiting its function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits JNK, a kinase in pathways linked to FAM169A, disrupting cellular processes involving the protein. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, a key player in FAM169A-associated pathways, disrupting cellular functions. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 inhibits MEK1, impacting signaling pathways connected to FAM169A and potentially inhibiting its activity. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad kinase inhibitor disrupting multiple signaling pathways, including those involving FAM169A. | ||||||
Calphostin C | 121263-19-2 | sc-3545 sc-3545A | 100 µg 1 mg | $336.00 $1642.00 | 20 | |
Calphostin C inhibits PKC, influencing downstream pathways associated with FAM169A and disrupting its function. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Bay 11-7082 inhibits NF-κB, a transcription factor in pathways connected to FAM169A, potentially inhibiting its expression. | ||||||