Date published: 2026-5-30

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FAM13A1 Inhibitors

FAM13A1 inhibitors belong to a specialized class of chemical compounds designed to target the FAM13A1 (Family with sequence similarity 13, member A1) protein. FAM13A1 is a relatively recently discovered gene associated with lung-related diseases and has been implicated in pulmonary disorders such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). This protein is thought to play a role in cellular processes related to lung tissue remodeling, inflammation, and fibrosis. While the exact functions and mechanisms of FAM13A1 are still being elucidated, research into FAM13A1 inhibitors is primarily focused on investigating the protein's roles in the context of lung health and disease. Inhibitors targeting FAM13A1 are designed to interact with the protein and modulate its activity, influencing the cellular processes it is involved in. The specific mechanisms by which these inhibitors interact with FAM13A1 and the consequences of their interaction are areas of ongoing research. Understanding the functions and regulation of FAM13A1 may provide valuable insights into the molecular pathways underlying lung diseases, paving the way for a deeper understanding of the disease mechanisms and potential avenues for further exploration.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

May suppress transcription broadly, potentially lowering the expression of a range of proteins, including FAM13A.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

Proteasome inhibitor; could cause accumulation of misfolded proteins and affect cellular signaling, indirectly reducing protein expression.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

Alters protein degradation pathways, which could lead to changes in the levels of transcription factors and gene expression.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

Inhibits PI3K, which is part of signaling pathways that can modulate transcription and protein expression.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor that can affect protein synthesis and potentially down-regulate certain gene expressions.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Inhibits JNK, which may affect transcription factor activity and result in altered expression profiles.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAPK, potentially affecting downstream transcription factors and gene expression.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

MEK inhibitor, which may lead to decreased ERK pathway signaling and could change gene expression patterns.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

PI3K inhibitor that could alter multiple signaling pathways and potentially impact gene expression.

ZM 336372

208260-29-1sc-202857
1 mg
$47.00
2
(1)

RAF kinase inhibitor that might modulate transcription factor activity downstream, influencing gene expression.