Date published: 2025-11-21

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Factor X Inhibitors

Factor X inhibitors belong to a chemical class of compounds that specifically target and inhibit the activity of factor X, also known as Stuart-Prower factor. Factor X is a crucial protein involved in the blood coagulation cascade, which is responsible for the formation of blood clots. The inhibitors act by interfering with the normal function of factor X, its role in the conversion of prothrombin to thrombin. Thrombin is essential for the final step in the clotting process, converting fibrinogen into fibrin, which forms the meshwork of a blood clot. The chemical structure of factor X inhibitors is designed to selectively bind to factor X, obstructing its active site or modulating its interactions with other proteins involved in the coagulation cascade. By inhibiting factor X, these compounds disrupt the clotting process and impede the formation of fibrin. This interference in the blood coagulation pathway can potentially have important implications in various contexts related to hemostasis and clotting disorders. As a class of compounds, factor X inhibitors are subject to ongoing research and development in the scientific community. Researchers aim to characterize their mechanisms of action, their specific interactions with factor X, and their potential impact on the clotting process. The ultimate goal of studying factor X inhibitors is to expand our understanding of the intricate mechanisms underlying blood coagulation, which could have implications in various fields of biology and biomedicine, though it is important to note that this description does not pertain to any or use of these compounds.

Items 1 to 10 of 16 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rivaroxaban

366789-02-8sc-208311
2 mg
$155.00
18
(1)

Rivaroxaban functions as a potent Factor Xa inhibitor, showcasing remarkable specificity in its interactions with the enzyme. Its unique structural features allow for effective binding within the active site, disrupting the coagulation cascade. The compound's conformational flexibility enhances its affinity, while its hydrophobic regions facilitate interactions with lipid membranes. Additionally, Rivaroxaban's kinetic profile reveals a rapid onset of action, underscoring its dynamic role in modulating enzymatic activity.

Apixaban

503612-47-3sc-364406
sc-364406A
10 mg
50 mg
$235.00
$622.00
2
(1)

Apixaban acts as a selective inhibitor of Factor Xa, characterized by its unique binding dynamics that stabilize the enzyme-inhibitor complex. Its distinct molecular architecture promotes strong interactions with key residues in the active site, effectively blocking substrate access. The compound exhibits a favorable pharmacokinetic profile, with a balanced distribution and elimination, allowing for predictable behavior in biological systems. Its solubility properties further enhance its interaction potential within various environments.

Sodium succinate dibasic

150-90-3sc-251053
100 g
$39.00
(0)

Sodium succinate dibasic functions as a versatile Factor X, exhibiting unique molecular interactions that facilitate its role in biochemical pathways. Its structure allows for effective coordination with metal ions, influencing reaction kinetics and enhancing catalytic efficiency. The compound's amphipathic nature contributes to its solubility in diverse environments, promoting interactions with various biomolecules. This behavior underscores its significance in modulating enzymatic activities and metabolic processes.

p-APMSF, Hydrochloride

74938-88-8sc-204155
sc-204155A
sc-204155B
sc-204155C
5 mg
10 mg
50 mg
100 mg
$85.00
$109.00
$299.00
$560.00
1
(1)

p-APMSF, Hydrochloride acts as a distinctive Factor X, characterized by its ability to form strong hydrogen bonds and hydrophobic interactions with target molecules. This compound exhibits selective reactivity, enabling it to modulate specific enzymatic pathways through competitive inhibition. Its unique electronic properties facilitate rapid reaction kinetics, while its solubility profile allows for effective integration into various biochemical systems, enhancing its role in molecular interactions.

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride

sc-220558
5 mg
$462.00
(0)

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride serves as a notable Factor X, distinguished by its capacity to engage in specific electrostatic interactions and conformational changes within target proteins. This compound demonstrates a unique affinity for active sites, promoting selective binding that influences downstream signaling pathways. Its structural features enable it to stabilize transient complexes, thereby affecting reaction dynamics and enhancing the specificity of molecular recognition events.

Gabexate mesylate

56974-61-9sc-215066
5 mg
$100.00
(0)

Gabexate mesylate acts as a Factor X, characterized by its ability to modulate proteolytic activity through selective inhibition of serine proteases. Its unique structure facilitates strong hydrogen bonding and hydrophobic interactions with target enzymes, altering their conformation and activity. This compound exhibits rapid kinetics in binding, allowing for effective competition with substrate molecules, ultimately influencing the cascade of coagulation processes at a molecular level.

Edoxaban

480449-70-5sc-483508
25 mg
$522.00
(0)

A direct factor Xa inhibitor used for DVT and PE, as well as to reduce the risk of stroke in atrial fibrillation.

GGACK

65113-67-9sc-201314
sc-201314A
sc-201314B
5 mg
25 mg
100 mg
$315.00
$1375.00
$5000.00
(1)

GGACK functions as a Factor X, distinguished by its capacity to interact with specific protein domains, leading to the modulation of coagulation pathways. Its unique molecular architecture promotes effective electrostatic interactions with target proteins, enhancing binding affinity. The compound exhibits a notable propensity for conformational changes in its targets, which can significantly impact enzymatic activity. Additionally, GGACK's reaction kinetics reveal a swift association and dissociation profile, influencing the dynamics of coagulation cascades.

Betrixaban

330942-05-7sc-503540
100 mg
$7500.00
(0)

A direct factor Xa inhibitor indicated for extended prophylaxis of venous thromboembolism (VTE)

Nafamostat mesylate

82956-11-4sc-201307
sc-201307A
10 mg
50 mg
$80.00
$300.00
4
(1)

Nafamostat mesylate acts as a Factor X through its ability to selectively inhibit serine proteases involved in the coagulation cascade. Its unique structure allows for precise interactions with the active sites of target enzymes, facilitating competitive inhibition. The compound demonstrates rapid kinetics, characterized by a fast onset of action and a short half-life, which can alter the balance of hemostatic processes. Its distinct binding dynamics contribute to the modulation of thrombin generation and fibrin formation.