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1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride is an effective irreversible inhibitor of Factor X (Factor Xa), and uPA (urokinase). The 1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride fluorophore allows direct monitoring of interactions of labeled enzymes. The compound does not inhibit tPA.
Bajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152. Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375. Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.
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