1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride MF: C26H36ClN7O7S•2HCl
MW: 699.1
An irreversible inhibitor of uPA, Factor X, and urokinase..

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride

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Application: An irreversible inhibitor of uPA, Factor X, and urokinase.
Molecular Weight: 699.1
Molecular Formula: C26H36ClN7O7S•2HCl
* Refer to Certificate of Analysis for lot specific data (including water content).

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride is an effective irreversible inhibitor of Factor X (Factor Xa), and uPA (urokinase). The 1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride fluorophore allows direct monitoring of interactions of labeled enzymes. The compound does not inhibit tPA.


References

Bajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 152. Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375. Kettner, C., and Shaw, E. 1981. Methods Enzymol. 80, 826.

Physical State :
Solid
Solubility :
Soluble in water, and 10 mM HCl.
Storage :
Store at 4° C
IC50 :
Factor Xa: IC50 = 100 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
SMILES :
CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)N[[email protected]@H](CCC(=O)O)C(=O)NCC(=O)N[[email protected]@H](CCCN=C(N)N)C(=O)CCl.Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

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