Sodium succinate dibasic CAS: 150-90-3
MF: C4H4Na2O4
MW: 162.05

Sodium succinate dibasic (CAS 150-90-3)

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Alternate Names: Succinic acid disodium salt; Disodium succinate
Application: An inhibitor of receptor tyrosine kinases
CAS Number: 150-90-3
Purity: ≥99%
Molecular Weight: 162.05
Molecular Formula: C4H4Na2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sodium succinate dibasic is an inhibitor of multiple receptor tyrosine kinases. Sodium succinate dibasic is known to be a potent inhibitor of Met, Flt-1 (VEGFR1), Flk-1 (VEGFR2), Flt-3 (VEGFR3), Ron, and Tie-2. Sodium succinate dibasic has been observed to inhibit Met (c-Met)-driven tumor cell and non-c-Met driven tumor cell (HCT116 and MDA-MB-231) proliferation. This product has also been observed to effectively inhibit c-Met phosphorylation and its downstream signaling pathways in serum starved MKN45 cells, as well as inducing apoptosis in these cells.

Appearance :
Crystalline powder
Physical State :
Solid
Storage :
Desiccate at room temperature
Melting Point :
>300° C
Density :
1.56 g/ml
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
WM4900000
PubChem CID :
Merck Index :
14: 8869
MDL Number :
MFCD00002790
EC Number :
205-778-7
Beilstein Registry :
1754069
SMILES :
C(CC(=O)[O-])C(=O)[O-].[Na+].[Na+]

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Certificate of Analysis

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