Ermin Inhibitors belong to a specialized class of chemical compounds designed to selectively impede the activity of the Ermin protein. Ermin is a cytoskeletal protein associated with neural tissues, particularly enriched in the central nervous system. It is a member of the actin-bundling protein family, contributing to the organization and stability of the actin cytoskeleton. Actin cytoskeleton plays a crucial role in various cellular processes, including cell morphology, intracellular transport, and cell signaling. The development of inhibitors targeting Ermin offers a valuable tool for scientific investigation, providing researchers with a means to probe the molecular functions and regulatory roles associated with this specific actin-binding protein.
The synthesis and optimization of Ermin inhibitors require a detailed understanding of the protein's structural characteristics and its interactions within the cytoskeletal network. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of Ermin and interfere with its normal actin-bundling activities. By employing Ermin inhibitors in experimental settings, researchers can explore the consequences of protein inhibition on cytoskeletal dynamics, shedding light on the specific cellular processes influenced by Ermin. The study of Ermin inhibitors contributes to the broader exploration of cytoskeletal regulation, providing insights into the intricate molecular machinery that underlies cellular morphology and the maintenance of structural integrity, particularly within neural tissues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D binds to DNA, inhibiting transcription and preventing the synthesis of Ermin mRNA. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide disrupts protein synthesis, leading to a reduction in Ermin expression by inhibiting translation. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $42.00 $214.00 $832.00 $66.00 | 394 | |
Puromycin induces premature termination of protein synthesis, impacting translation and lowering Ermin levels. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampicin inhibits bacterial RNA polymerase, indirectly suppressing Ermin expression by interfering with transcription. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin hinders protein synthesis by blocking peptidyl transferase activity, leading to reduced Ermin synthesis. | ||||||
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Cordycepin interferes with mRNA synthesis, impacting transcription and contributing to the downregulation of Ermin. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $69.00 $266.00 | 8 | |
Mycophenolic acid inhibits inosine monophosphate dehydrogenase, indirectly affecting Ermin expression by disrupting purine synthesis. | ||||||
Blasticidin S Hydrochloride | 3513-03-9 | sc-204655A sc-204655 | 25 mg 100 mg | $367.00 $520.00 | 20 | |
Blasticidin S induces premature termination during translation, inhibiting protein synthesis and reducing Ermin levels. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
5-Fluorouracil interferes with RNA synthesis, affecting the expression of Ermin by disrupting the production of mRNA. | ||||||