ERI-1 Activators
ERI-1 activators encompass a range of compounds that influence various cellular processes, leading to indirect effects on the exonuclease activity of ERI-1. These chemicals primarily modulate the RNAi pathway, DNA damage response, gene expression through epigenetic alterations, and the stability of RNA molecules, thereby affecting the activity of ERI-1 by altering its substrate pool.
Inhibitors of enzymes like ATM and DNA methyltransferases may result in changes in RNA processing and stability, influencing the availability and turnover of RNA molecules that are substrates for ERI-1. In contrast, compounds such as Genistein and Lithium Chloride, which act on signal transduction and Wnt signaling respectively, can have downstream effects on RNA transcription and stability, indirectly modulating ERI-1's role in RNAi.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ATM Kinase Inhibitor | 587871-26-9 | sc-202963 | 2 mg | $110.00 | 28 | |
An ATM inhibitor that can affect DNA damage response pathways, potentially altering RNA processing and stability, indirectly modulating ERI-1 activity by changing the availability of RNA substrates. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Similar to 5-Azacytidine, this compound incorporates into DNA and affects methylation patterns, which can indirectly lead to alterations in RNA transcript levels and may influence ERI-1 substrate availability. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
A DNA methyltransferase inhibitor that can change gene expression profiles, including those of small RNAs that could be substrates for ERI-1. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $129.00 $284.00 $1004.00 | 3 | |
Another DNA methyltransferase inhibitor that can alter RNA expression and stability, possibly influencing ERI-1 activity by affecting its RNA substrates. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor that can modulate signal transduction pathways, potentially leading to changes in RNA transcription and stability, thereby affecting ERI-1 activity. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $184.00 $668.00 | 2 | |
As a methyl donor, SAMe is involved in methylation processes that can alter RNA transcription and turnover, potentially influencing ERI-1 activity by altering the pool of RNA substrates. | ||||||
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | $139.00 $663.00 | 2 | |
A synthetic analog of double-stranded RNA that can activate RNAi pathways and thereby potentially influence the activity of proteins like ERI-1 that are involved in these pathways. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Can impact Wnt signaling pathway and as a consequence, may affect RNA processing pathways, indirectly influencing the activity of RNA processing enzymes such as ERI-1. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
An inhibitor of histone deacetylases that can change chromatin structure and gene expression, potentially affecting RNA processing and the activity of enzymes such as ERI-1 by modifying the pool of RNA substrates. | ||||||