eRF3a Inhibitors
The inhibitors listed above primarily target various steps of protein synthesis, which could indirectly influence eRF3a activity. Given eRF3a's role in translation termination, modulation of protein synthesis processes is relevant for understanding its function and potential regulation. Cycloheximide, Puromycin, Anisomycin, and Emetine disrupt different stages of protein synthesis in eukaryotic cells, potentially affecting eRF3a's function in translation termination. Ricin and Diphtheria Toxin, by inactivating ribosomes or elongation factors, could indirectly impact eRF3a's role.
Compounds like Chloramphenicol and Tetracycline, which target bacterial protein synthesis, might also influence mitochondrial translation and indirectly eRF3a. Sordarin and Homoharringtonine, targeting fungal and eukaryotic translation initiation or elongation, respectively, could indirectly affect eRF3a. Sparsomycin, inhibiting peptide bond formation, might influence the termination phase involving eRF3a.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
Cycloheximide inhibits eukaryotic protein synthesis by interfering with the translocation step, potentially affecting processes involving eRF3a. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin inhibits peptide bond formation, potentially influencing the termination phase where eRF3a is involved. | ||||||
Emetine | 483-18-1 | sc-470668 sc-470668A sc-470668B sc-470668C | 1 mg 10 mg 50 mg 100 mg | $440.00 $900.00 $1400.00 $2502.00 | ||
Emetine inhibits protein synthesis by blocking the movement of ribosomes along mRNA, potentially affecting eRF3a activity. | ||||||
Geneticin (G418) Sulfate | 108321-42-2 | sc-29065 sc-29065A sc-29065C sc-29065D sc-29065B | 1 g 5 g 100 g 500 g 25 g | $108.00 $399.00 $1530.00 $6248.00 $469.00 | 193 | |
G418 interferes with protein synthesis in eukaryotic cells, potentially impacting the function of eRF3a. | ||||||
Chloramphenicol | 56-75-7 | sc-3594 | 25 g | $90.00 | 10 | |
Chloramphenicol inhibits bacterial protein synthesis but may also affect mitochondrial protein synthesis, indirectly impacting eRF3a. | ||||||
Diphtheria Toxin, CRM Mutant | 92092-36-9 | sc-203924 | 0.25 mg | $652.00 | 1 | |
Diphtheria toxin inhibits eukaryotic protein synthesis by ADP-ribosylating elongation factor 2, potentially influencing eRF3a function. | ||||||
Sordarin sodium salt | 463356-00-5 | sc-253601 | 5 mg | $557.00 | 2 | |
Sordarin inhibits fungal protein synthesis by targeting elongation factor 2, which might indirectly affect eRF3a in fungi. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $52.00 $125.00 $182.00 | 11 | |
Homoharringtonine inhibits protein synthesis initiation, potentially impacting the termination phase where eRF3a functions. | ||||||
Tetracycline | 60-54-8 | sc-205858 sc-205858A sc-205858B sc-205858C sc-205858D | 10 g 25 g 100 g 500 g 1 kg | $63.00 $94.00 $270.00 $417.00 $634.00 | 6 | |
Tetracycline inhibits bacterial protein synthesis, but may also affect mitochondrial translation, indirectly impacting eRF3a. | ||||||