Date published: 2026-5-13

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ER alpha Inhibitors

Santa Cruz Biotechnology now offers a broad range of ER alpha Inhibitors for use in various applications. ER alpha inhibitors are a category of compounds that specifically target and modulate the activity of the estrogen receptor alpha (ERα), a nuclear hormone receptor involved in the transcriptional regulation of various genes. These inhibitors are pivotal in research focused on understanding the role of estrogen signaling in cellular processes. By selectively inhibiting ERα, researchers can study its direct effects on gene expression profiles, cellular proliferation, and differentiation in a variety of cell types. This approach is particularly valuable in the study of hormone-driven mechanisms in cellular models, providing insights into cellular responses under controlled experimental conditions. ER alpha inhibitors have been utilized in a broad spectrum of research areas, including developmental biology, cancer research, and cellular physiology. They help in dissecting the pathways that are modulated by estrogen receptors and contribute significantly to our understanding of cell function and gene regulation mechanisms. These inhibitors are crucial tools for researchers looking to study the complex signaling pathways influenced by hormonal changes and their implications on cellular behavior. With the use of ER alpha inhibitors, the scientific community has advanced its knowledge on how specific changes in receptor activity affect cellular outcomes, paving the way for further research in cellular regulation and signaling. View detailed information on our available ER alpha Inhibitors by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

ICI 182,780

129453-61-8sc-203435
sc-203435A
1 mg
10 mg
$83.00
$187.00
34
(1)

ICI 182,780 is a selective estrogen receptor degrader (SERD) that works by binding to the estrogen receptor and promoting its degradation, leading to a decrease in estrogen signaling.

Anastrozole

120511-73-1sc-217647
10 mg
$92.00
1
(1)

Anastrozole is an aromatase inhibitor that reduces the production of estrogen by inhibiting the aromatase enzyme.

Letrozole

112809-51-5sc-204791
sc-204791A
25 mg
50 mg
$87.00
$147.00
5
(1)

Letrozole is another aromatase inhibitor that works similarly to anastrozole by reducing estrogen production.

Exemestane

107868-30-4sc-203045
sc-203045A
25 mg
100 mg
$134.00
$411.00
(0)

Exemestane is an aromatase inhibitor that irreversibly binds to the aromatase enzyme, blocking estrogen synthesis.

Tamoxifen

10540-29-1sc-208414
2.5 g
$272.00
18
(2)

Although not a direct ESR1 inhibitor, tamoxifen is a selective estrogen receptor modulator (SERM) that competes with estrogen for binding to the estrogen receptor, effectively blocking estrogen's actions.

Raloxifene

84449-90-1sc-476458
1 g
$802.00
3
(0)

Similar to tamoxifen, raloxifene is a SERM that has antiestrogenic effects on breast tissue.