Anastrozole (CAS 120511-73-1)

Anastrozole is an organic chemical compound that belongs to the class of compounds known as aromatase inhibitors. Chemically, it is characterized by a specific molecular structure that allows it to interact with the enzyme aromatase, which plays a key role in the biosynthesis of estrogens from androgens. Anastrozole′s ability to inhibit this enzyme arises from its structure, making it a subject of interest in the study of enzyme inhibition and hormonal synthesis pathways. The compound has a molecular formula of C17H19N5 and features a triazole ring, a key functional group that contributes to its mechanism of action at the molecular level. This triazole ring is linked to a benzyl group, which is substituted with an anilino moiety, adding to the complexity of its interactions with biological molecules. Anastrozole is synthesized through a series of organic reactions that involve the construction of the triazole ring and the subsequent attachment of the benzyl and anilino groups. The synthesis and study of anastrozole and similar compounds are of interest in organic chemistry for their insights into ring formation, functional group chemistry, and the principles of enzyme inhibition.