Epigen Activators
Epigen Activators are a class of compounds that directly support the functional activity of Epigen through methylation processes or by influencing the availability of substrates and cofactors required for Epigen's role in epigenetic regulation. S-Adenosyl methionine and SAMe, for instance, are primary methyl donors in biological methylation reactions, providing the necessary methyl groups that Epigen utilizes to modify histones and DNA. The presence of these compounds directly correlates with the heightened activity of Epigen in the nucleus, where it partakes in the dynamic regulation of gene expression through methylation.
Compounds such as 5-Aza-2'-deoxycytidine and Decitabine are DNA methyltransferase inhibitors and function by reducing DNA methylation levels, which can lead to the upregulation of genes that are otherwise silenced. This hypomethylation can result in an increased expression of Epigen and subsequently enhance its activity in the nucleus. Additionally, the availability of methyl donors and cofactors like Folic Acid, Methylcobalamin, Betaine, and Choline is crucial for the methylation cycle. These compounds contribute to the one-carbon metabolism and methionine synthesis pathways, ensuring that Epigen has a consistent supply of substrates to facilitate its methylation activity. Zinc, serving as a cofactor, and Vitamin B6, as part of amino acid metabolism, play supportive roles in the biochemical pathways that underpin Epigen's function, thereby enhancing its regulatorycapacity. Retinoic Acid, being an epigenetic modulator that influences gene expression, can also enhance the activity of Epigen by affecting the chromatin structure. Genistein's inhibition of tyrosine kinases alters cell signaling pathways, which can indirectly lead to the activation of Epigen due to changes in cell growth and differentiation signals.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $180.00 $655.00 | 2 | |
Donor of methyl groups required for methylation processes, directly influencing the activity of Epigen by providing necessary substrates for histone and DNA methylation, which Epigen is directly involved in. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A DNA methyltransferase inhibitor that leads to hypomethylation of DNA. This hypomethylation can result in the upregulation of genes, including those that code for Epigen, enhancing its presence and activity in the nucleus. | ||||||
Mecobalamin | 13422-55-4 | sc-211781 | 10 mg | $300.00 | ||
A form of vitamin B12 used as a cofactor in methylation reactions. It contributes to the methylation cycle where Epigen is involved, thus enhancing its methylation activity. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $30.00 $40.00 $55.00 $160.00 $330.00 $580.00 | 2 | |
Methyl donor in the methionine cycle and can donate methyl groups to assist in the methylation processes where Epigen is active, enhancing its function in epigenetic regulation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Isoflavone that acts as a tyrosine kinase inhibitor, which can indirectly enhance the methylation process by affecting signaling pathways that regulate cell growth and differentiation, processes where Epigen is known to be involved. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
A key molecule in the one-carbon metabolism pathway, which is essential for the production of methyl groups used in methylation processes that Epigen can utilize, thus enhancing its activity. | ||||||
Pyridoxine Hydrochloride | 58-56-0 | sc-219674 | 10 mg | $41.00 | ||
Coenzyme in reactions of amino acid metabolism that can influence methylation reactions. It plays a role in the synthesis of substrates necessary for methylation, which can enhance the functional activity of Epigen. | ||||||
Choline chloride | 67-48-1 | sc-207430 sc-207430A sc-207430B | 10 mg 5 g 50 g | $32.00 $36.00 $51.00 | 1 | |
A methyl donor in the biosynthesis of methionine, which is a precursor for S-Adenosyl methionine. Choline's contribution to this pathway enhances the availability of methyl donors for Epigen's methylation activity. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Essential mineral that acts as a cofactor for DNA methylation enzymes. Zinc's presence is critical for the proper function of enzymes that Epigen interacts with, thus influencing its activity in epigenetic regulation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Metabolite of vitamin A that regulates gene expression through epigenetic mechanisms, which can enhance the activity of Epigen as it is directly involved in the modification of chromatin structure. | ||||||