Emerin activators are a group of chemical compounds that have garnered attention in the field of molecular biology and cell biology due to their unique ability to modulate the activity of the protein emerin. Emerin is a key structural protein found in the inner nuclear membrane of eukaryotic cells, and it plays a crucial role in maintaining the structural integrity of the nucleus. It is particularly important in mediating nuclear envelope-cytoskeleton interactions and contributes to the overall stability of the cell's nuclear architecture. The discovery of emerin activators has opened up exciting avenues of research for understanding the molecular mechanisms governing nuclear envelope dynamics and their impact on cellular functions.
These emerin activators are designed to specifically target and enhance the function of emerin. While the exact mechanisms of action may vary among different activators, they typically work by binding to emerin and promoting its stability or facilitating its interactions with other nuclear envelope proteins. This enhanced functionality of emerin can have a profound impact on various cellular processes, including nuclear positioning, chromatin organization, and signal transduction. Moreover, by modulating emerin activity, these compounds offer a unique tool for investigating the broader implications of nuclear envelope biology in health and disease. Researchers are actively exploring the effects of emerin activators on cellular processes and how they might be utilized to gain insights into fundamental aspects of cell biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
This compound is a DNA methylation inhibitor that may enhance emerin expression by altering chromatin structure and making the EMD gene more accessible for transcription. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
This compound has histone deacetylase inhibitory activity, potentially enhancing emerin expression through epigenetic modifications. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate acts as a histone deacetylase inhibitor, possibly increasing emerin expression by promoting a more relaxed chromatin state. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can regulate gene expression through its role as a ligand for retinoic acid receptors, potentially influencing emerin expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG has various biological activities, including epigenetic modulation, which may contribute to the upregulation of emerin expression. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3, through its active form, interacts with vitamin D receptors to regulate gene expression, potentially influencing emerin levels. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol has been shown to influence gene expression and has potential epigenetic modulation activities that could affect emerin expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin has antioxidant properties and has been shown to influence gene expression, potentially modulating emerin levels. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine influences various cellular processes and could potentially play a role in the regulation of emerin expression. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
This compound has been studied for its ability to modulate gene expression, and it may have a role in influencing emerin expression. | ||||||