ELOVL4 activators consist of a diverse array of chemicals, each contributing to the efficient functioning of the ELOVL4 enzyme responsible for the elongation of long-chain fatty acids. Essential fatty acids such as Linoleic acid, DHA, and Arachidonic acid serve as key substrates for ELOVL4, allowing the protein to achieve its role in fatty acid elongation. EPA, Palmitic acid, and Stearic acid similarly act as substrates, confirming their position as central figures in the chain elongation process. Their direct involvement emphasizes the importance of these fatty acids in ensuring ELOVL4 remains active.
Furthermore, chemicals that indirectly modulate the expression or function of ELOVL4 expand the scope of potential activators. Retinoic acid, by impacting the transcriptional regulation of genes tied to fatty acid metabolism, can indirectly drive ELOVL4's activity. This principle is also echoed with chemicals like thiazolidinediones, which, by acting as PPARγ agonists, can stimulate transcriptional mechanisms supporting ELOVL4. Notably, cAMP and insulin play more generalized roles in metabolic pathways, with their potential to indirectly buttress ELOVL4 functionality.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Linoleic Acid | 60-33-3 | sc-200788 sc-200788A sc-200788B sc-200788C | 100 mg 1 g 5 g 25 g | $34.00 $64.00 $166.00 $281.00 | 4 | |
Linoleic acid serves as a substrate for ELOVL4, promoting its enzymatic activity in fatty acid elongation. | ||||||
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $94.00 $210.00 $1779.00 $8021.00 $16657.00 | 11 | |
DHA can be a substrate and also promote the synthesis of very long-chain fatty acids via ELOVL4. | ||||||
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $92.00 $240.00 $4328.00 | 9 | |
Acts as a substrate for ELOVL4, promoting its role in fatty acid elongation. | ||||||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) | 10417-94-4 | sc-200766 sc-200766A | 100 mg 1 g | $104.00 $431.00 | ||
Can be a substrate for ELOVL4, enhancing the production of long-chain fatty acids. | ||||||
Palmitic Acid | 57-10-3 | sc-203175 sc-203175A | 25 g 100 g | $114.00 $286.00 | 2 | |
Serves as a substrate for ELOVL4, leading to the elongation of fatty acids. | ||||||
Stearic Acid | 57-11-4 | sc-203408 sc-203408A sc-203408B | 100 g 1 kg 5 kg | $26.00 $32.00 $117.00 | 1 | |
Initiates fatty acid elongation through serving as an ELOVL4 substrate. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Can influence the transcriptional activity of genes involved in fatty acid metabolism, including ELOVL4. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
Can modulate pathways that increase the expression and activity of ELOVL4. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Regulates metabolic pathways, potentially enhancing ELOVL4 function indirectly. | ||||||