Date published: 2025-11-24

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Elmo Inhibitors

Elmo Inhibitors are a class of chemical compounds that play a crucial role in cellular signaling pathways and have garnered significant attention in the field of molecular biology and pharmacology. These inhibitors are designed to target a specific protein called Engulfment and Motility protein(Elmo), which is a vital regulator of cellular processes such as phagocytosis, cell migration, and cytoskeletal reorganization. Elmo itself acts as an essential adaptor protein in various signaling cascades, serving as a bridge between cell surface receptors and downstream effectors. By inhibiting the activity of Elmo, these compounds modulate intracellular signaling events, leading to alterations in cellular behavior and function. Elmo inhibitors typically function by binding to specific sites on the Elmo protein, disrupting its interactions with other signaling molecules. This interference can have profound effects on cellular processes. For example, in the context of phagocytosis, the inhibition of Elmo can hinder the engulfment of foreign particles or pathogens by immune cells, thereby affecting the body's defense mechanisms. Moreover, Elmo is involved in cell migration, which is essential for various physiological processes, including tissue development and wound healing. By targeting Elmo, these inhibitors can influence cell motility and, consequently, tissue repair and morphogenesis. Overall, Elmo inhibitors represent a valuable tool for researchers seeking to understand the intricacies of cellular signaling pathways and their potential applications beyond the realm of therapy.

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Imatinib

152459-95-5sc-267106
sc-267106A
sc-267106B
10 mg
100 mg
1 g
$25.00
$117.00
$209.00
27
(1)

Inhibits tyrosine kinases, particularly BCR-ABL, thereby blocking signaling pathways in leukemia cells.

Gefitinib

184475-35-2sc-202166
sc-202166A
sc-202166B
sc-202166C
100 mg
250 mg
1 g
5 g
$62.00
$112.00
$214.00
$342.00
74
(2)

Targets and inhibits the epidermal growth factor receptor (EGFR), disrupting cell proliferation and survival in cancer.

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$56.00
$260.00
$416.00
129
(3)

Inhibits multiple kinases like Raf and VEGFR, reducing angiogenesis and tumor cell growth in various cancers.

MDV3100

915087-33-1sc-364354
sc-364354A
5 mg
50 mg
$240.00
$1030.00
7
(1)

Acts as an androgen receptor antagonist, blocking the binding of androgens and hindering prostate cancer cell growth.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Histone deacetylase (HDAC) inhibitor, altering chromatin structure and gene expression in cancer cells, leading to apoptosis.

Everolimus

159351-69-6sc-218452
sc-218452A
5 mg
50 mg
$128.00
$638.00
7
(1)

mTOR inhibitor that disrupts the PI3K/AKT/mTOR pathway, suppressing cell proliferation and angiogenesis in cancer.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$132.00
$1064.00
115
(2)

Proteasome inhibitor, preventing protein degradation, and inducing apoptosis in multiple myeloma and other cancers.

Erlotinib, Free Base

183321-74-6sc-396113
sc-396113A
sc-396113B
sc-396113C
sc-396113D
500 mg
1 g
5 g
10 g
100 g
$85.00
$132.00
$287.00
$495.00
$3752.00
42
(0)

Targets EGFR kinase, interfering with cell signaling pathways to inhibit tumor growth, primarily in lung cancer.

Palbociclib

571190-30-2sc-507366
50 mg
$315.00
(0)

CDK4/6 inhibitor, arresting cell cycle progression in hormone receptor-positive breast cancer and other malignancies.

Olaparib

763113-22-0sc-302017
sc-302017A
sc-302017B
250 mg
500 mg
1 g
$206.00
$299.00
$485.00
10
(1)

PARP inhibitor, disrupting DNA repair in BRCA-mutated cancer cells, leading to DNA damage accumulation and cell death.