eIF5AL1 Activators
eIF5AL1 activators represent a diverse class of chemicals that interact with various signaling pathways and cellular processes to potentially influence the activity of eIF5AL1. These activators do not directly target eIF5AL1 but affect the cellular environment and signaling networks in which eIF5AL1 operates. This indirect mode of action highlights the complexity of cellular signaling and the intricate regulation of protein synthesis.
For example, insulin and metformin, through their effects on the PI3K/AKT/mTOR and AMPK pathways respectively, create a cellular context that can modulate the activity of eIFs, including eIF5AL1. This modulation primarily occurs through the regulation of mTOR, a central regulator of protein synthesis. Similarly, compounds like U0126 and LY294002, which target the MAPK/ERK and PI3K pathways, respectively, alter signaling cascades that can indirectly impact eIF5AL1. Resveratrol and curcumin, known for their roles in modulating cellular stress responses and inflammation, also potentially influence eIF5AL1 through these broad cellular effects.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Activates the PI3K/AKT/mTOR pathway, which is known to enhance protein synthesis by influencing eIFs, potentially affecting eIF5AL1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR, indirectly affecting eIFs including eIF5AL1 by altering the balance of protein synthesis. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
Activates AMPK, which can modulate mTOR signaling, indirectly influencing eIF5AL1 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor, indirectly modulates the AKT/mTOR pathway, influencing eIF5AL1. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Activates SIRT1, influencing cellular stress responses that can indirectly affect eIF5AL1. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Modulates various signaling pathways, including NF-kB, which can indirectly influence eIF5AL1 activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Influences various signaling pathways and can modulate cellular stress responses, potentially affecting eIF5AL1. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Histone deacetylase inhibitor, affects gene expression, potentially influencing eIF5AL1. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Glucocorticoid receptor agonist, modulates inflammatory pathways, potentially influencing eIF5AL1. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Stimulates cAMP, potentially influencing pathways that affect eIF5AL1. | ||||||