Egr-3 Activators belong to a class of chemical compounds designed to modulate the activity of early growth response protein 3 (Egr-3), also known as zinc finger protein 333 (Zfp-333). Egr-3 is a transcription factor that plays a significant role in the regulation of gene expression in response to various cellular signals and environmental cues. It is part of the early growth response (Egr) family of transcription factors, which also includes Egr-1 and Egr-2. Egr-3 is expressed in various tissues, including the nervous system, immune system, and skeletal muscle. Egr-3 Activators are synthesized with the intent of selectively interacting with Egr-3, influencing its DNA-binding affinity, transcriptional activity, or protein-protein interactions, although the specific mechanisms can vary among different compounds within this chemical class.
The activation of Egr-3 by these compounds can lead to changes in gene expression patterns, affecting various cellular processes and functions. Egr-3 typically acts as a transcriptional regulator by binding to specific DNA sequences and modulating the transcription of target genes. Egr-3 is involved in a wide range of biological processes, including cell growth, differentiation, apoptosis, immune responses, and nervous system development. Egr-3 Activators serve as valuable tools for scientists studying the intricate mechanisms of gene regulation and the roles of Egr-3 in cellular and physiological processes. However, it's important to note that the specific mechanisms and outcomes of Egr-3 activation may vary depending on the context and the particular compound used within this chemical class, as Egr-3's functions are highly context-dependent and can vary among different cell types and tissues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels and potentially modulating transcription factors including Egr-3. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC), influencing signaling pathways leading to Egr-3 activation. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
A calcium ionophore that increases intracellular calcium, potentially affecting Egr-3 expression pathways. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Inhibits TGF-β signaling, potentially affecting Egr-3. | ||||||