EGFLAM, also known as EGF-like, fibronectin type III, and laminin G domains, is a multifaceted protein encoded by the EGFLAM gene in humans. This protein is part of the extracellular matrix (ECM), a complex network of proteins and molecules that provide structural and biochemical support to surrounding cells. EGFLAM is characterized by having several domains common to proteins involved in cell adhesion and signaling, including epidermal growth factor (EGF)-like domains, which are known for their role in cell growth and development, fibronectin type III domains that are frequently involved in cell adhesion and receptor binding, and laminin G domains that are important for cell attachment, migration, and neurite outgrowth.
The precise biological functions of EGFLAM are not fully elucidated, but it is believed to be involved in the processes of cell adhesion, migration, and cellular signaling, which are critical during development. Its expression in muscle and the central nervous system suggests a role in the development and maintenance of these tissues. EGFLAM may facilitate the interactions between cells and the ECM, influencing pathways that govern cell differentiation, proliferation, and communication.Given its structural roles and involvement in signaling pathways, EGFLAM is of interest in research related to muscle and neurological development, as well as in studies of diseases where cell adhesion and ECM interactions are disrupted.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
May regulate gene expression through retinoic acid receptors, potentially affecting EGFLAM. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Elevates cAMP, which may modulate transcription factors and influence EGFLAM expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Glucocorticoids can regulate gene expression, potentially altering EGFLAM levels. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C, which may lead to transcriptional regulation of EGFLAM. | ||||||
Sodium Salicylate | 54-21-7 | sc-3520 sc-3520A sc-3520B sc-3520C | 1 g 25 g 500 g 1 kg | $10.00 $26.00 $82.00 $139.00 | 8 | |
Inhibits NF-κB signaling, potentially influencing EGFLAM transcription. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Modulates transcription factors and signaling pathways, which may alter EGFLAM expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences GSK-3 signaling, potentially affecting EGFLAM expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Estrogen receptor signaling can impact gene expression, possibly including EGFLAM. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
PPAR agonists modulate the expression of genes involved in metabolism and inflammation, potentially affecting EGFLAM. | ||||||
25-Hydroxycholesterol | 2140-46-7 | sc-214091B sc-214091 sc-214091A sc-214091C | 5 mg 10 mg 25 mg 100 mg | $53.00 $91.00 $169.00 $474.00 | 8 | |
Oxysterols regulate lipid metabolism and may influence genes involved in lipid signaling pathways, including EGFLAM. | ||||||