Date published: 2026-4-1

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EG665615 Inhibitors

EG665615 inhibitors represent a class of small molecules designed to specifically target and modulate the function of certain proteins or enzymes within a biological pathway. These compounds typically operate by binding to active or regulatory sites on their target protein, altering the protein's conformation or activity. Structurally, EG665615 inhibitors often feature complex aromatic and aliphatic substitutions that allow for high specificity and selectivity in binding. The inhibitors may possess a central scaffold to which various side chains are appended, optimizing their ability to interact with key amino acid residues in their target binding sites. Such chemical structures can be fine-tuned to achieve optimal physical and chemical properties, such as solubility, permeability, and stability, which are essential for their effectiveness as inhibitors. The inhibitors may interact via reversible or irreversible mechanisms, and their binding affinity can vary, often reflected in parameters such as dissociation constant (Kd) or half-maximal inhibitory concentration (IC50).

These inhibitors are often used in biochemical and cellular assays to dissect the function of the target protein, providing insights into underlying biological processes. By blocking or modulating the activity of specific enzymes or pathways, EG665615 inhibitors enable researchers to study the mechanistic basis of various cellular responses. Additionally, their high specificity makes them valuable tools in molecular biology for investigating signal transduction, protein-protein interactions, and other key regulatory mechanisms. Characterization of these inhibitors involves rigorous analytical techniques, including structural elucidation using NMR or mass spectrometry, assessment of binding affinities through surface plasmon resonance (SPR) or isothermal titration calorimetry (ITC), and functional assays to determine their effects on target activity. The versatility and specificity of EG665615 inhibitors make them important components in the exploration and understanding of complex biochemical pathways and molecular mechanisms in various fields of research.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Finasteride

98319-26-7sc-203954
50 mg
$105.00
3
(1)

Inhibits 5-alpha-reductase, reducing the conversion of testosterone to dihydrotestosterone, thus decreasing androgen signaling that can regulate Smr2l expression.

Flutamide

13311-84-7sc-204757
sc-204757A
sc-204757D
sc-204757B
sc-204757C
1 g
5 g
25 g
500 g
1 kg
$47.00
$156.00
$171.00
$525.00
$941.00
4
(1)

Acts as an androgen receptor antagonist, blocking androgen receptor signaling and subsequent Smr2l activation.

Bicalutamide

90357-06-5sc-202976
sc-202976A
100 mg
500 mg
$42.00
$146.00
27
(1)

Competes with androgens for androgen receptor binding sites, inhibiting the activation of Smr2l.

MDV3100

915087-33-1sc-364354
sc-364354A
5 mg
50 mg
$245.00
$1051.00
7
(1)

Obstructs androgen receptor signaling by inhibiting nuclear translocation of the receptor and Smr2l transcriptional activity.

Apalutamide

956104-40-8sc-507442
5 mg
$290.00
(0)

Prevents androgen receptor translocation and DNA binding, reducing Smr2l transcription.

Ketoconazole

65277-42-1sc-200496
sc-200496A
50 mg
500 mg
$63.00
$265.00
21
(1)

Inhibits steroidogenesis, including androgen synthesis, thereby decreasing Smr2l expression through reduced androgen availability.

Abiraterone

154229-19-3sc-460288
10 mg
$276.00
(0)

Inhibits cytochrome P450 17A1, leading to decreased androgen synthesis and downregulation of Smr2l expression.

Dutasteride

164656-23-9sc-207600
10 mg
$167.00
2
(1)

Inhibits both isoforms of 5-alpha-reductase, leading to a significant decrease in dihydrotestosterone and reduced Smr2l expression.

Cyproterone

2098-66-0sc-278913
sc-278913A
sc-278913B
sc-278913C
sc-278913D
25 mg
50 mg
100 mg
250 mg
1 g
$153.00
$235.00
$296.00
$439.00
$1173.00
(1)

Competes with androgens for receptor sites and inhibits the receptor's interaction with DNA, reducing Smr2l expression.

Spironolactone

52-01-7sc-204294
50 mg
$109.00
3
(1)

Functions as an androgen receptor antagonist and decreases androgen production, which can suppress Smr2l expression.