Molecular structure of Cyproterone, CAS Number: 2098-66-0
Cyproterone (CAS 2098-66-0)
Alternate Names:
Ciproterona
CAS Number:
2098-66-0
Molecular Weight:
374.91
Molecular Formula:
C22H27ClO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Cyproterone, a synthetic steroidal anti-androgen, exhibits potent antineoplastic properties. In its acetate form, Cyproterone interacts with the androgen receptor (AR), effectively halting androgen-triggered receptor activation and curtailing the growth of testosterone-sensitive tumor cells. Notably, it also exerts progesterogenic activity, leading to diminished testicular androgen secretion and comprehensive androgen blockade.
Cyproterone (CAS 2098-66-0) References
- Structural determinants of developmental toxicity in hamsters. | Gómez, J., et al. 1999. Teratology. 60: 190-205. PMID: 10508972
- Structure-activity relationships of synthetic progestins in a yeast-based in vitro androgen bioassay. | McRobb, L., et al. 2008. J Steroid Biochem Mol Biol. 110: 39-47. PMID: 18395441
- Update on genotoxicity and carcinogenicity testing of 472 marketed pharmaceuticals. | Brambilla, G. and Martelli, A. 2009. Mutat Res. 681: 209-229. PMID: 18845271
- Genotoxicity and carcinogenicity testing of pharmaceuticals: correlations between induction of DNA lesions and carcinogenic activity. | Brambilla, G., et al. 2010. Mutat Res. 705: 20-39. PMID: 20206292
- Leveraging existing data for prioritization of the ecological risks of human and veterinary pharmaceuticals to aquatic organisms. | LaLone, CA., et al. 2014. Philos Trans R Soc Lond B Biol Sci. 369: PMID: 25405975
- European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters. | Tousova, Z., et al. 2017. Sci Total Environ. 601-602: 1849-1868. PMID: 28629112
- Characterizing cleft palate toxicants using ToxCast data, chemical structure, and the biomedical literature. | Baker, NC., et al. 2020. Birth Defects Res. 112: 19-39. PMID: 31471948
- Estrogenic potency of endocrine disrupting chemicals and their mixtures detected in environmental waters and wastewaters. | Durcik, M., et al. 2023. Chemosphere. 330: 138712. PMID: 37068617
- Teratogenesis: a statistical structure-activity model. | Enslein, K., et al. 1983. Teratog Carcinog Mutagen. 3: 289-309. PMID: 6137085
- Development of a pH-paralleling approach of quantifying six-category pharmaceuticals in surface water using SPE-HPLC-MS/MS | Hong, B., Yu, S., Zhou, M., Li, J., Ding, J., & Niu, Y. 2021. Watershed Ecology and the Environment. 3: 1-16.
Inhibitor of:
DEXI, EG665615, Progesterone, and PSA.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cyproterone, 25 mg | sc-278913 | 25 mg | $153.00 | |||
Cyproterone, 50 mg | sc-278913A | 50 mg | $235.00 | |||
Cyproterone, 100 mg | sc-278913B | 100 mg | $296.00 | |||
Cyproterone, 250 mg | sc-278913C | 250 mg | $439.00 | |||
Cyproterone, 1 g | sc-278913D | 1 g | $1173.00 |