Gm4988, a predicted gene with putative DNA-binding transcription factor activity, is intricately linked to RNA polymerase II-specific regulatory functions, marking its significance in cellular transcriptional control. Positioned as a central player in gene regulation, Gm4988's primary function revolves around influencing the intricate orchestration of RNA polymerase II-mediated processes. Predicted to possess DNA-binding transcription factor activity, Gm4988's role likely extends to the modulation of gene expression by directly engaging with regulatory DNA sequences.
The activation of Gm4988 involves a complex interplay of various chemical modulators, each targeting specific cellular pathways that indirectly impact its DNA-binding transcription factor activity and RNA polymerase II-specific regulatory functions. These pathways, including retinoic acid signaling, histone modification, cAMP elevation, and MAPK cascades, contribute to the nuanced regulation of Gm4988. The interplay between these chemical modulators and Gm4988 reveals a sophisticated network of activation mechanisms that highlight the adaptability of Gm4988 to respond to diverse intracellular signals and environmental cues. The intricate regulatory dynamics underscore the importance of Gm4988 in fine-tuning cellular transcriptional processes, shedding light on the complexities of gene expression regulation within the cellular milieu.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Up-regulates Gm4988 by binding to retinoic acid receptors, influencing RNA polymerase II-specific regulatory functions. Enhances DNA binding. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
HDAC inhibitor impacting chromatin structure, indirectly promoting Gm4988. Enhances RNA polymerase II-specific regulatory functions. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Alters histone acetylation, promoting Gm4988 function. Influences RNA polymerase II-specific regulatory functions, enhancing DNA-binding. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
BET inhibitor affecting bromodomain proteins, promoting Gm4988 activity. Modulates chromatin structure, enhancing RNA polymerase II regulation. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 (free base) | sc-202651 | 5 mg | $148.00 | 4 | |
G9a inhibitor affecting histone methylation, promoting Gm4988 function. Modulates epigenetic marks, enhancing RNA polymerase II regulatory functions. | ||||||
NSC 668036 | 144678-63-7 | sc-507412 | 5 mg | $175.00 | ||
Dvl PDZ domain inhibitor impacting Wnt signaling, indirectly promoting Gm4988. Alters Dishevelled function, enhancing RNA polymerase II binding. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Enhances Gm4988 activity by activating SIRT1, influencing RNA polymerase II-specific regulatory functions. Modulates cellular pathways, promoting DNA binding. | ||||||