Date published: 2025-10-10

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EF-CAB2 Activators

The chemical class denoted as EF-CAB2 Activators encompasses a specific group of compounds known for their ability to modulate the activity of the EF-CAB2 gene. EF-CAB2, or Elongation Factor-Cation Channel Complex Subunit B2, represents a gene encoding a protein involved in the elongation phase of protein synthesis. This gene product plays a crucial role in forming a complex with the elongation factor EF-1 alpha and a calcium channel, facilitating the entry of calcium ions into the cell during protein synthesis. While the exact function of EF-CAB2 is not fully elucidated, it is believed to contribute to the regulation of protein synthesis and possibly participate in calcium signaling pathways within the cell. Activators of EF-CAB2 are substances capable of enhancing the expression or function of this gene, potentially influencing downstream cellular pathways and biological responses associated with its activity.

Characterizing compounds as EF-CAB2 Activators typically involves comprehensive screening processes aimed at evaluating their ability to interact with regulatory elements of the EF-CAB2 gene or modulate the activity of proteins associated with its expression or function. These activators may operate through diverse mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for EF-CAB2 gene expression, or modulating post-translational modifications of the EF-CAB2 protein. Understanding the molecular mechanisms underlying EF-CAB2 activation by these compounds is crucial for elucidating the roles of EF-CAB2 in cellular physiology and protein synthesis regulation. Further research into EF-CAB2 Activators may provide insights into novel cellular pathways and contribute to a deeper understanding of EF-CAB2's function in cellular homeostasis and protein synthesis.

SEE ALSO...

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Verapamil

52-53-9sc-507373
1 g
$367.00
(0)

A calcium channel blocker that may indirectly affect the expression of calcium-binding proteins with EF-hand domains by altering intracellular calcium levels.

Nifedipine

21829-25-4sc-3589
sc-3589A
1 g
5 g
$58.00
$170.00
15
(1)

This compound, by modulating L-type calcium channels, may influence cellular calcium homeostasis and thus potentially affect the expression of EF-hand domain-containing proteins.

Amlodipine

88150-42-9sc-200195
sc-200195A
100 mg
1 g
$73.00
$163.00
2
(1)

As a calcium channel antagonist, it may alter calcium dynamics in cells, potentially impacting the expression of proteins with EF-hand calcium-binding domains.

Diltiazem

42399-41-7sc-204726
sc-204726A
1 g
5 g
$209.00
$464.00
4
(1)

By blocking calcium influx through calcium channels, this compound may indirectly modulate the expression of calcium-dependent proteins with EF-hand domains.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$94.00
$349.00
114
(2)

A SERCA pump inhibitor that disrupts calcium homeostasis, which might influence the expression of EF-hand domain proteins.

Cyclopiazonic Acid

18172-33-3sc-201510
sc-201510A
10 mg
50 mg
$173.00
$612.00
3
(1)

An inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA), potentially affecting calcium signaling and the expression of EF-hand domain proteins.

Ryanodine

15662-33-6sc-201523
sc-201523A
1 mg
5 mg
$219.00
$765.00
19
(2)

Modulates the release of calcium from the sarcoplasmic reticulum, which may indirectly influence the expression of EF-hand domain-containing proteins.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
5 g
100 g
250 g
1 kg
5 kg
$32.00
$66.00
$95.00
$188.00
$760.00
13
(1)

By affecting calcium release channels in the sarcoplasmic reticulum, it may impact calcium signaling and potentially the expression of EF-hand domain proteins.

2-APB

524-95-8sc-201487
sc-201487A
20 mg
100 mg
$27.00
$52.00
37
(1)

Modulates intracellular calcium release channels and may influence the expression of proteins with EF-hand calcium-binding domains.

TMB-8 • HCl

53464-72-5sc-3522
sc-3522A
10 mg
50 mg
$42.00
$126.00
10
(1)

Interferes with intracellular calcium release and might affect the expression of EF-hand domain-containing proteins.