EBV EBNA-2 Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $156.00 | 5 | |
BTK inhibitor that disrupts BCR signaling pathway, which is crucial for EBV latency and EBNA-2 expression, thereby directly inhibiting EBV EBNA-2 activity. | ||||||
ABT-199 | 1257044-40-8 | sc-472284 sc-472284A sc-472284B sc-472284C sc-472284D | 1 mg 5 mg 10 mg 100 mg 3 g | $118.00 $337.00 $520.00 $832.00 $1632.00 | 10 | |
BCL-2 inhibitor that induces apoptosis in EBV-infected cells, leading to downregulation of EBNA-2 expression and inhibition of its oncogenic functions. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Proteasome inhibitor that prevents degradation of IκBα, resulting in inhibition of NF-κB pathway activation and subsequent suppression of EBV EBNA-2 transcription. | ||||||
CAL-101 | 870281-82-6 | sc-364453 | 10 mg | $193.00 | 4 | |
PI3K inhibitor that blocks PI3K/Akt/mTOR pathway, leading to downregulation of EBNA-2 expression and inhibition of its pro-survival and proliferative functions. | ||||||
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $251.00 $500.00 $547.00 | 16 | |
JAK inhibitor that suppresses JAK/STAT pathway, resulting in decreased expression of EBNA-2 and inhibition of EBV-mediated B-cell transformation and proliferation. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
SRC inhibitor that disrupts cellular signaling cascades involved in EBV EBNA-2 expression and downstream oncogenic activities, leading to direct inhibition of EBNA-2. | ||||||
Dinaciclib | 779353-01-4 | sc-364483 sc-364483A | 5 mg 25 mg | $247.00 $888.00 | 1 | |
CDK inhibitor that blocks cell cycle progression and downregulates EBNA-2 expression, thereby inhibiting EBV-mediated B-cell immortalization and transformation. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
HDAC inhibitor that induces chromatin remodeling and downregulation of EBNA-2 transcription, leading to inhibition of EBV latent gene expression and viral replication. | ||||||
MDV3100 | 915087-33-1 | sc-364354 sc-364354A | 5 mg 50 mg | $245.00 $1051.00 | 7 | |
Androgen receptor antagonist that inhibits EBNA-2 expression by interfering with androgen receptor-mediated transcriptional activation, leading to direct inhibition. | ||||||
Trametinib | 871700-17-3 | sc-364639 sc-364639A sc-364639B | 5 mg 10 mg 1 g | $114.00 $166.00 $947.00 | 19 | |
MEK inhibitor that disrupts MAPK signaling pathway, resulting in decreased expression of EBNA-2 and inhibition of its oncogenic functions in EBV-infected cells. | ||||||