DUSP27 activators comprise an array of chemical compounds that directly or indirectly enhance the functional activity of DUSP27. Activators of this class play a role in modifying the phosphorylation state of DUSP27, thereby augmenting its functional activity. Similarly, they increases cAMP levels and stimulates PKA. This surge in PKA activity can influence the phosphorylation state of DUSP27, enhancing its function. Activators lead to a less suppressed ERK pathway, which can alter the phosphorylation state of DUSP27 and enhance its function.
DUSP27 activators activate SIRT1, a protein known to modulate the function of various proteins through deacetylation. The activation of SIRT1 can alter the acetylation state of DUSP27, leading to enhanced function. Activators of this class can increase SIRT1 activity and enhance DUSP27 function. DUSP27 activators lead to a less suppressed AKT pathway when PI3K is inhibited. This can alter the phosphorylation state of DUSP27 and enhance its function. By suppression of the PI3K pathway, activators atler the phosphorylation state of DUSP27 and enhancing its function. Finally, activators can lead to changes in the activity of the AKT/PI3K pathway. This can also modify the phosphorylation state of DUSP27, thereby enhancing its function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin is an activator of adenylate cyclase, leading to increased cAMP levels and potential activation of PKA. Elevated PKA activity can affect the phosphorylation state of DUSP27, thereby enhancing its function. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates SIRT1, which is known to regulate the function of various proteins through deacetylation. SIRT1 activation can potentially alter the acetylation state of DUSP27, leading to its enhanced function. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $61.00 $122.00 | 1 | |
Niacin is a precursor of NAD+, which is a co-factor for SIRT1. Increased SIRT1 activity can potentially alter the acetylation state of DUSP27, enhancing its function. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Triciribine is an AKT inhibitor. When AKT is inhibited, the PI3K pathway is less suppressed, which can alter the phosphorylation state of DUSP27 and enhance its function. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin activates SIRT1, which is known to regulate the function of various proteins through deacetylation. SIRT1 activation can potentially alter the acetylation state of DUSP27, leading to its enhanced function. | ||||||