The chemical class known as Mitochondrial thiamine pyrophosphate carrier (TPC) Activators comprises a group of compounds that have the potential to influence TPC indirectly by modulating mitochondrial function and associated pathways. These compounds have been identified due to their roles in cellular energy metabolism and mitochondrial health. TPC is a crucial transporter responsible for thiamine pyrophosphate (TPP) transport into mitochondria, an essential step in mitochondrial energy production. While direct activators of TPC may not be well-documented, these activators can indirectly impact TPC by supporting mitochondrial processes. Many of the compounds in this class, such as thiamine (Vitamin B1), nicotinamide riboside (NR), and creatine, provide essential substrates or precursors that contribute to mitochondrial function and energy metabolism. These compounds can enhance the cellular machinery that supports efficient TPC activity.
Additionally, other activators, like resveratrol, alpha-lipoic acid, and Coenzyme Q10 (CoQ10), have demonstrated benefits for mitochondrial health and function, potentially influencing TPC by creating an environment conducive to its activity. Furthermore, the indirect activators of TPC are involved in crucial cellular pathways, including AMP-activated protein kinase (AMPK), PGC-1α, and NAD+ metabolism, which can positively impact mitochondrial biogenesis and energy production. Collectively, the Mitochondrial thiamine pyrophosphate carrier (TPC) Activators chemical class represents a range of compounds that can play a significant role in supporting the cellular mechanisms underlying TPC function and mitochondrial health. In summary, the compounds in the Mitochondrial thiamine pyrophosphate carrier (TPC) Activators class have the potential to enhance TPC indirectly by promoting mitochondrial health and cellular energy metabolism. These compounds, some of which are vital nutrients, can create an environment where TPC can operate efficiently, contributing to overall mitochondrial function and energy production. While the specific effects on TPC require further research and validation, these activators offer promising avenues for understanding and potentially modulating mitochondrial processes in which TPC plays a crucial role.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Vitamin B1 | 59-43-8 | sc-338735 | 5 g | $611.00 | ||
Precursor of thiamine pyrophosphate (TPP), which supports TPC function. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Known for its effects on mitochondrial health, it may indirectly affect TPC through mitochondrial pathways. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
An antioxidant with potential benefits for mitochondrial health, which may influence TPC activity indirectly. | ||||||
Creatine, anhydrous | 57-00-1 | sc-214774 sc-214774A | 10 mg 50 g | $27.00 $77.00 | 2 | |
Involved in cellular energy metabolism and could impact mitochondrial function, indirectly affecting TPC. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Essential for mitochondrial energy production, it may have indirect effects on TPC. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $33.00 $77.00 $175.00 | 3 | |
Involved in fatty acid transport into mitochondria, potentially influencing mitochondrial function and TPC. | ||||||
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $32.00 $42.00 $62.00 $108.00 $184.00 $724.00 $2050.00 | 2 | |
An intermediate in the citric acid cycle, related to mitochondrial metabolism. | ||||||
Dichloroacetic acid | 79-43-6 | sc-214877 sc-214877A | 25 g 100 g | $60.00 $125.00 | 5 | |
Affects mitochondrial metabolism, potentially impacting TPC indirectly. | ||||||
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $238.00 | ||
Involved in mitochondrial biogenesis and function, potentially influencing TPC. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
An antidiabetic agent in research that can impact mitochondrial function and may indirectly affect TPC. | ||||||