Date published: 2025-11-24

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DNC Activators

The chemical class known as Mitochondrial thiamine pyrophosphate carrier (TPC) Activators comprises a group of compounds that have the potential to influence TPC indirectly by modulating mitochondrial function and associated pathways. These compounds have been identified due to their roles in cellular energy metabolism and mitochondrial health. TPC is a crucial transporter responsible for thiamine pyrophosphate (TPP) transport into mitochondria, an essential step in mitochondrial energy production. While direct activators of TPC may not be well-documented, these activators can indirectly impact TPC by supporting mitochondrial processes. Many of the compounds in this class, such as thiamine (Vitamin B1), nicotinamide riboside (NR), and creatine, provide essential substrates or precursors that contribute to mitochondrial function and energy metabolism. These compounds can enhance the cellular machinery that supports efficient TPC activity.

Additionally, other activators, like resveratrol, alpha-lipoic acid, and Coenzyme Q10 (CoQ10), have demonstrated benefits for mitochondrial health and function, potentially influencing TPC by creating an environment conducive to its activity. Furthermore, the indirect activators of TPC are involved in crucial cellular pathways, including AMP-activated protein kinase (AMPK), PGC-1α, and NAD+ metabolism, which can positively impact mitochondrial biogenesis and energy production. Collectively, the Mitochondrial thiamine pyrophosphate carrier (TPC) Activators chemical class represents a range of compounds that can play a significant role in supporting the cellular mechanisms underlying TPC function and mitochondrial health. In summary, the compounds in the Mitochondrial thiamine pyrophosphate carrier (TPC) Activators class have the potential to enhance TPC indirectly by promoting mitochondrial health and cellular energy metabolism. These compounds, some of which are vital nutrients, can create an environment where TPC can operate efficiently, contributing to overall mitochondrial function and energy production. While the specific effects on TPC require further research and validation, these activators offer promising avenues for understanding and potentially modulating mitochondrial processes in which TPC plays a crucial role.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Vitamin B1

59-43-8sc-338735
5 g
$611.00
(0)

Precursor of thiamine pyrophosphate (TPP), which supports TPC function.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Known for its effects on mitochondrial health, it may indirectly affect TPC through mitochondrial pathways.

α-Lipoic Acid

1077-28-7sc-202032
sc-202032A
sc-202032B
sc-202032C
sc-202032D
5 g
10 g
250 g
500 g
1 kg
$68.00
$120.00
$208.00
$373.00
$702.00
3
(1)

An antioxidant with potential benefits for mitochondrial health, which may influence TPC activity indirectly.

Creatine, anhydrous

57-00-1sc-214774
sc-214774A
10 mg
50 g
$27.00
$77.00
2
(0)

Involved in cellular energy metabolism and could impact mitochondrial function, indirectly affecting TPC.

Coenzyme Q10

303-98-0sc-205262
sc-205262A
1 g
5 g
$70.00
$180.00
1
(1)

Essential for mitochondrial energy production, it may have indirect effects on TPC.

L-Carnitine

541-15-1sc-205727
sc-205727A
sc-205727B
sc-205727C
1 g
5 g
100 g
250 g
$23.00
$33.00
$77.00
$175.00
3
(1)

Involved in fatty acid transport into mitochondria, potentially influencing mitochondrial function and TPC.

α-Ketoglutaric Acid

328-50-7sc-208504
sc-208504A
sc-208504B
sc-208504C
sc-208504D
sc-208504E
sc-208504F
25 g
100 g
250 g
500 g
1 kg
5 kg
16 kg
$32.00
$42.00
$62.00
$108.00
$184.00
$724.00
$2050.00
2
(1)

An intermediate in the citric acid cycle, related to mitochondrial metabolism.

Dichloroacetic acid

79-43-6sc-214877
sc-214877A
25 g
100 g
$60.00
$125.00
5
(0)

Affects mitochondrial metabolism, potentially impacting TPC indirectly.

Pyrroloquinoline quinone

72909-34-3sc-210178
1 mg
$238.00
(1)

Involved in mitochondrial biogenesis and function, potentially influencing TPC.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$42.00
$62.00
$153.00
$255.00
$500.00
$30.00
37
(1)

An antidiabetic agent in research that can impact mitochondrial function and may indirectly affect TPC.