Dlx-5 Activators
Dlx-5 activators represent a diverse array of chemicals that play a pivotal role in modulating the activity of Dlx-5, a transcription factor crucial for skeletal development. The direct activators, including Chrysin, Icariin, Puerarin, Genistein, Kaempferol, Quercetin, Rutin, Biochanin A, Oroxylin A, and Formononetin, act by directly promoting the phosphorylation of Dlx-5, enhancing its transcriptional activity, and positively regulating the expression of genes associated with skeletal development. These chemicals exemplify the specificity of their action, directly influencing Dlx-5 function to orchestrate downstream skeletal gene expression. In addition to direct activators, compounds like Carnosic Acid, Dioscin, and Emodin serve as indirect activators by modulating specific signaling pathways involved in Dlx-5 activation. Carnosic Acid enhances Wnt/β-catenin signaling, Dioscin influences the BMP pathway, and Emodin modulates the TGF-β pathway. These indirect activators showcase the intricate regulatory mechanisms through which Dlx-5 activation is influenced, providing a nuanced understanding of the pathways involved in skeletal development.
The comprehensive profile of Dlx-5 activators underscores the role of these chemicals in elucidating the molecular mechanisms governing skeletal gene expression. As pivotal players in the intricate network controlling Dlx-5, these activators offer valuable tools for investigating and understanding the pathways involved in skeletal development. Further exploration of their specific impacts on Dlx-5 activity could unveil novel insights into the regulatory landscape of skeletal gene expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Chrysin | 480-40-0 | sc-204686 | 1 g | $37.00 | 13 | |
Chrysin, a natural flavonoid, serves as a direct activator of Dlx-5 by promoting its phosphorylation and enhancing its transcriptional activity. This phosphorylation positively regulates the expression of genes associated with skeletal development, emphasizing the role of Chrysin in directly modulating Dlx-5 function and influencing downstream skeletal gene expression. | ||||||
Icariin | 489-32-7 | sc-279198 sc-279198A sc-279198B | 1 g 5 g 10 g | $142.00 $413.00 $814.00 | ||
Icariin, a natural compound found in Epimedium plants, acts as a direct activator of Dlx-5 by enhancing its phosphorylation and subsequent activation. This activation positively regulates the expression of genes crucial for skeletal development, highlighting Icariin's role in directly modulating Dlx-5 and influencing downstream skeletal gene expression. | ||||||
Carnosic acid | 3650-09-7 | sc-202520 sc-202520A | 10 mg 50 mg | $60.00 $165.00 | 6 | |
Carnosic Acid, a natural phenolic diterpene, serves as an indirect activator of Dlx-5 by modulating the Wnt/β-catenin signaling pathway. It enhances the Wnt pathway, leading to increased Dlx-5 activation and subsequent upregulation of genes involved in skeletal development. The modulation of Wnt/β-catenin signaling by Carnosic Acid illustrates its specific mechanism for indirectly activating Dlx-5 and influencing downstream skeletal gene expression. | ||||||
Puerarin | 3681-99-0 | sc-202301 sc-202301A | 5 mg 100 mg | $129.00 $205.00 | 1 | |
Puerarin, an isoflavone found in kudzu root, acts as a direct activator of Dlx-5 by promoting its phosphorylation and enhancing its transcriptional activity. This phosphorylation positively regulates the expression of genes associated with skeletal development, emphasizing the role of Puerarin in directly modulating Dlx-5 function and influencing downstream skeletal gene expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a naturally occurring isoflavone, serves as a direct activator of Dlx-5 by promoting its phosphorylation and subsequent activation. This activation positively regulates the expression of genes crucial for skeletal development, highlighting the role of Genistein in directly modulating Dlx-5 and influencing downstream skeletal gene expression. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $97.00 $212.00 $500.00 | 11 | |
Kaempferol, a natural flavonoid, serves as a direct activator of Dlx-5 by promoting its phosphorylation and enhancing its transcriptional activity. This phosphorylation positively regulates the expression of genes associated with skeletal development, emphasizing the role of Kaempferol in directly modulating Dlx-5 function and influencing downstream skeletal gene expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid abundant in fruits and vegetables, acts as a direct activator of Dlx-5 by promoting its phosphorylation and subsequent activation. This activation positively regulates the expression of genes crucial for skeletal development, highlighting the role of Quercetin in directly modulating Dlx-5 and influencing downstream skeletal gene expression. | ||||||
Rutin trihydrate | 250249-75-3 | sc-204897 sc-204897A sc-204897B | 5 g 50 g 100 g | $56.00 $71.00 $124.00 | 7 | |
Rutin, a flavonoid glycoside, serves as a direct activator of Dlx-5 by promoting its phosphorylation and enhancing its transcriptional activity. This phosphorylation positively regulates the expression of genes associated with skeletal development, emphasizing the role of Rutin in directly modulating Dlx-5 function and influencing downstream skeletal gene expression. | ||||||
Dioscin | 19057-60-4 | sc-497470 | 25 mg | $380.00 | ||
Dioscin, a natural steroid saponin, acts as an indirect activator of Dlx-5 by modulating the BMP signaling pathway. It enhances BMP signaling, leading to increased Dlx-5 activation and subsequent upregulation of genes involved in skeletal development. The modulation of BMP signaling by Dioscin illustrates its specific mechanism for indirectly activating Dlx-5 and influencing downstream skeletal gene expression. | ||||||
Biochanin A | 491-80-5 | sc-205603 sc-205603A | 100 mg 250 mg | $75.00 $129.00 | ||
Biochanin A, a naturally occurring isoflavone, serves as a direct activator of Dlx-5 by promoting its phosphorylation and enhancing its transcriptional activity. This phosphorylation positively regulates the expression of genes associated with skeletal development, emphasizing the role of Biochanin A in directly modulating Dlx-5 function and influencing downstream skeletal gene expression. | ||||||