Dia 1 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Latrunculin A binds to actin monomers, preventing their polymerization. By disrupting actin filament formation, it indirectly inhibits Dia1's role in actin organization and cell motility. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Cytochalasin D inhibits actin polymerization by binding to the barbed ends of actin filaments. This action can indirectly hinder Dia1's function in actin dynamics and cellular processes like migration. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $89.00 $262.00 | 13 | |
ML-7 is an inhibitor of myosin light chain kinase (MLCK). By inhibiting MLCK, it affects the actin-myosin interaction, indirectly inhibiting Dia1-related actin cytoskeletal reorganization. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $71.00 $260.00 $485.00 $949.00 | ||
Blebbistatin inhibits myosin II ATPase activity. This inhibition can alter the actomyosin dynamics, potentially inhibiting Dia1-mediated processes. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 is a Rho-associated protein kinase (ROCK) inhibitor. Since Dia1 is regulated by Rho GTPases, inhibiting ROCK can indirectly inhibit Dia1's function in actin filament stabilization and cell morphology. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $315.00 $1020.00 | 5 | |
CK-666 is an inhibitor of the Arp2/3 complex, which is involved in branched actin network formation. By inhibiting Arp2/3 complex, it can indirectly inhibit Dia1's function in coordinating actin assembly. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
SMIFH2 inhibits formin-mediated actin nucleation and elongation. As Dia1 is a formin, this inhibitor can indirectly hinder its actin polymerization function. | ||||||
CCG-1423 | 285986-88-1 | sc-205241 sc-205241A | 1 mg 5 mg | $30.00 $90.00 | 8 | |
CCG-1423 inhibits RhoA-mediated gene transcription. Since Dia1 activity is modulated by RhoA, inhibiting this pathway can indirectly inhibit Dia1's function in actin cytoskeletal dynamics. | ||||||
Rhosin | 1173671-63-0 | sc-507401 | 25 mg | $555.00 | ||
Rhosin is a selective inhibitor of RhoA subfamily GTPases. By inhibiting RhoA, it can indirectly inhibit Dia1 activity, which is regulated by RhoA-mediated signaling. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $30.00 $87.00 $132.00 $434.00 | 13 | |
Simvastatin, a HMG-CoA reductase inhibitor, can affect the prenylation and function of small GTPases. This effect can indirectly inhibit Dia1 activity, as small GTPases are involved in its regulation. | ||||||