Molecular structure of Rhosin, CAS Number: 1173671-63-0
Rhosin (CAS 1173671-63-0)
Alternate Names:
G04
CAS Number:
1173671-63-0
Molecular Weight:
358.405
Molecular Formula:
C20H18N6O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rhosin (CAS 1173671-63-0) References
- Rational design of small molecule inhibitors targeting RhoA subfamily Rho GTPases. | Shang, X., et al. 2012. Chem Biol. 19: 699-710. PMID: 22726684
- The Selective RhoA Inhibitor Rhosin Promotes Stress Resiliency Through Enhancing D1-Medium Spiny Neuron Plasticity and Reducing Hyperexcitability. | Francis, TC., et al. 2019. Biol Psychiatry. 85: 1001-1010. PMID: 30955841
- RhoA inhibitor-eluting stent attenuates restenosis by inhibiting YAP signaling. | Huang, C., et al. 2019. J Vasc Surg. 69: 1581-1589.e1. PMID: 31010523
- Rational design of small molecule RHOA inhibitors for gastric cancer. | Kim, JH., et al. 2020. Pharmacogenomics J. 20: 601-612. PMID: 32015453
- Rhosin Suppressed Tumor Cell Metastasis through Inhibition of Rho/YAP Pathway and Expression of RHAMM and CXCR4 in Melanoma and Breast Cancer Cells. | Tsubaki, M., et al. 2021. Biomedicines. 9: PMID: 33406809
- Small chemical compounds Y16 and Rhosin can inhibit calcium sensitization pathway in vascular smooth muscle cells of spontaneously hypertensive rats. | Chiu, WC., et al. 2021. J Formos Med Assoc. 120: 1863-1868. PMID: 33893012
- Activation mechanism dependent surface exposure of cellular factor XIII on activated platelets and platelet microparticles. | Somodi, L., et al. 2022. J Thromb Haemost. 20: 1223-1235. PMID: 35146910
- The role of Astragalus polysaccharides in promoting IEC-6 cell migration from polyamine-mediated Ca2+ regulation. | Zhang, D., et al. 2022. Int J Biol Macromol. 207: 179-192. PMID: 35217086
- Structure-Activity Relationship Analysis of Rhosin, a RhoA GTPase Inhibitor, Reveals a New Class of Antiplatelet Agents. | Dandamudi, A., et al. 2023. Int J Mol Sci. 24: PMID: 36835579
- Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation. | Medica, S., et al. 2023. PLoS Pathog. 19: e1011682. PMID: 37782657
Inhibitor of:
4931406P16Rik, A430078G23Rik, A730069N07Rik, ARHGAP (Rho GTPase activating protein), ARHGAP11B, ARHGAP12, ARHGAP15, ARHGAP21, ARHGAP23, ARHGAP4, ARHGEF10L, ARHGEF17, ARHGEF19, ARHGEF37, ARHGEF39, ARHGEF5_Arhgef5, ARHGEF9, ARL4D, Atlastin, C8orf80, C9orf100, Cdc42, Cdc42EP3, CdGAP, DBC-2, DIRAS2, Drac1/2, E130112L23Rik, Ect2, Elmo1, FGD5, FGD6, FILIA, FRMD3, Gα 13, Gbp9, LARG, Lbc, Ly-GDI, Ly6/uPAR (LYNX; Ly6/neurotoxin), MCF2L2, MRCKγ, MYH9, NET1, Olfr876, Olfr877, Olfr878, OTTMUSG00000005723, PLEK2, PLEKHG3, PLEKHG5, PLEKHG6, RGNEF, Rho A, Rho B, Rho C, Rho F, Rho G, Rho GAP p190, Rho GDI, Rho GDIα, Rho H, Rho J, Rho T1, RHOBTB1, RhoGEF p115_Lsc, Rhotekin, RILPL1, Rnd1, Rock-1, SLIT-ROBO Rho GTPase activating protein (SRGAP), SYDE1, Tau-2, TBC1D13, TC10, Whirlin, WRCH1, and Zizimin-1.Activator of:
A430078G23Rik, ARHGAP10, ARHGAP11A, ARHGAP24, ARHGAP30, ARHGAP36, ARHGAP40, ARHGAP6, ARHGEF38, DAAM2, Las17, PARD6B, PDZ-RhoGEF, and SPATA13.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rhosin, 25 mg | sc-507401 | 25 mg | $555.00 |