Date published: 2025-9-10

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DHRS7C Activators

DHRS7C activators are compounds that enhance the activity of DHRS7C by affecting the retinoid signaling pathway or providing more substrates for DHRS7C to metabolize. The compounds identified here, including all-trans retinoic acid, 9-cis retinoic acid, fenretinide, isotretinoin, retinyl acetate, acitretin, tretinoin, ethanol, adapalene, bexarotene, alitretinoin, and retinyl palmitate, interact with the retinoid signaling pathway and can be metabolized by DHRS7C. By providing more substrate for DHRS7C, these compounds enhance the functional activity of this enzyme. This is crucial for the metabolism of retinoids, an essential process in maintaining cellular processes such as cell growth, differentiation, and apoptosis.

For instance, compounds like all-trans retinoic acid and 9-cis retinoic acid are naturally occurring retinoids, and synthetic retinoids like fenretinide, isotretinoin, acitretin, tretinoin, adapalene, bexarotene, and alitretinoin also enhance the activity of DHRS7C. By providing more substrate for this enzyme, these compounds enhance its functional activity, whichis vital for the metabolism of retinoids. Retinyl acetate and retinyl palmitate, forms of vitamin A, are also metabolized by DHRS7C, thus providing more substrates for the enzyme to act upon. Ethanol, a small molecule that can be metabolized in the liver, also impacts the retinoid signaling pathway and can be metabolized by DHRS7C, enhancing its functional activity by providing more substrate.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

All-trans retinoic acid (ATRA) is involved in the regulation of lipid metabolism and can impact the retinoid signaling pathway. DHRS7C is known to interact with retinoids and metabolize them, so the presence of ATRA can increase the activity of DHRS7C by providing more substrate for it to metabolize.

9-cis-Retinoic acid

5300-03-8sc-205589
sc-205589B
sc-205589C
sc-205589D
sc-205589A
1 mg
25 mg
250 mg
500 mg
5 mg
$70.00
$416.00
$3060.00
$5610.00
$145.00
10
(1)

9-cis retinoic acid is another variant of retinoic acid. It also interacts with the retinoid signaling pathway and can be metabolized by DHRS7C, enhancing its functional activity by providing more substrate.

4-Hydroxyphenylretinamide

65646-68-6sc-200900
sc-200900A
5 mg
25 mg
$104.00
$315.00
(0)

Fenretinide is a synthetic retinoid derivative that can be metabolized by DHRS7C. It interacts with the retinoid signaling pathway, and its presence enhances the functional activity of DHRS7C by providing an additional substrate.

13-cis-Retinoic acid

4759-48-2sc-205568
sc-205568A
100 mg
250 mg
$74.00
$118.00
8
(1)

Isotretinoin is a synthetic retinoid that is known to interact with the retinoid signaling pathway. By providing more substrate for DHRS7C, it enhances the functional activity of this enzyme.

Acitretin

55079-83-9sc-210754
25 mg
$148.00
1
(1)

Acitretin is a retinoid studied in the research of psoriasis. It interacts with the retinoid signaling pathway and provides DHRS7C with a substrate to metabolize, thereby enhancing its activity.

Adapalene

106685-40-9sc-203803
sc-203803A
10 mg
50 mg
$65.00
$325.00
2
(0)

Adapalene is a synthetic retinoid analogue that can be metabolized by DHRS7C. Its interaction with the retinoid signaling pathway provides DHRS7C with an additional substrate, enhancing its activity.

Bexarotene

153559-49-0sc-217753
sc-217753A
10 mg
100 mg
$54.00
$245.00
6
(1)

Bexarotene is a synthetic retinoid that can be metabolized by DHRS7C. It interacts with the retinoid signaling pathway and provides the enzyme with more substrate, enhancing its activity.