DHRS7C activators are compounds that enhance the activity of DHRS7C by affecting the retinoid signaling pathway or providing more substrates for DHRS7C to metabolize. The compounds identified here, including all-trans retinoic acid, 9-cis retinoic acid, fenretinide, isotretinoin, retinyl acetate, acitretin, tretinoin, ethanol, adapalene, bexarotene, alitretinoin, and retinyl palmitate, interact with the retinoid signaling pathway and can be metabolized by DHRS7C. By providing more substrate for DHRS7C, these compounds enhance the functional activity of this enzyme. This is crucial for the metabolism of retinoids, an essential process in maintaining cellular processes such as cell growth, differentiation, and apoptosis.
For instance, compounds like all-trans retinoic acid and 9-cis retinoic acid are naturally occurring retinoids, and synthetic retinoids like fenretinide, isotretinoin, acitretin, tretinoin, adapalene, bexarotene, and alitretinoin also enhance the activity of DHRS7C. By providing more substrate for this enzyme, these compounds enhance its functional activity, whichis vital for the metabolism of retinoids. Retinyl acetate and retinyl palmitate, forms of vitamin A, are also metabolized by DHRS7C, thus providing more substrates for the enzyme to act upon. Ethanol, a small molecule that can be metabolized in the liver, also impacts the retinoid signaling pathway and can be metabolized by DHRS7C, enhancing its functional activity by providing more substrate.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
All-trans retinoic acid (ATRA) is involved in the regulation of lipid metabolism and can impact the retinoid signaling pathway. DHRS7C is known to interact with retinoids and metabolize them, so the presence of ATRA can increase the activity of DHRS7C by providing more substrate for it to metabolize. | ||||||
9-cis-Retinoic acid | 5300-03-8 | sc-205589 sc-205589B sc-205589C sc-205589D sc-205589A | 1 mg 25 mg 250 mg 500 mg 5 mg | $70.00 $416.00 $3060.00 $5610.00 $145.00 | 10 | |
9-cis retinoic acid is another variant of retinoic acid. It also interacts with the retinoid signaling pathway and can be metabolized by DHRS7C, enhancing its functional activity by providing more substrate. | ||||||
4-Hydroxyphenylretinamide | 65646-68-6 | sc-200900 sc-200900A | 5 mg 25 mg | $104.00 $315.00 | ||
Fenretinide is a synthetic retinoid derivative that can be metabolized by DHRS7C. It interacts with the retinoid signaling pathway, and its presence enhances the functional activity of DHRS7C by providing an additional substrate. | ||||||
13-cis-Retinoic acid | 4759-48-2 | sc-205568 sc-205568A | 100 mg 250 mg | $74.00 $118.00 | 8 | |
Isotretinoin is a synthetic retinoid that is known to interact with the retinoid signaling pathway. By providing more substrate for DHRS7C, it enhances the functional activity of this enzyme. | ||||||
Acitretin | 55079-83-9 | sc-210754 | 25 mg | $148.00 | 1 | |
Acitretin is a retinoid studied in the research of psoriasis. It interacts with the retinoid signaling pathway and provides DHRS7C with a substrate to metabolize, thereby enhancing its activity. | ||||||
Adapalene | 106685-40-9 | sc-203803 sc-203803A | 10 mg 50 mg | $65.00 $325.00 | 2 | |
Adapalene is a synthetic retinoid analogue that can be metabolized by DHRS7C. Its interaction with the retinoid signaling pathway provides DHRS7C with an additional substrate, enhancing its activity. | ||||||
Bexarotene | 153559-49-0 | sc-217753 sc-217753A | 10 mg 100 mg | $54.00 $245.00 | 6 | |
Bexarotene is a synthetic retinoid that can be metabolized by DHRS7C. It interacts with the retinoid signaling pathway and provides the enzyme with more substrate, enhancing its activity. |