DHH1 Activators
DHH1 is a DEAD-box RNA helicase primarily studied in the yeast Saccharomyces cerevisiae. It is part of a family of proteins known for their role in various aspects of RNA metabolism, including mRNA decay, translation, and the dynamic regulation of RNA-protein complexes. DHH1 plays a crucial role in the post-transcriptional regulation of gene expression, impacting cellular responses and adaptation to various conditions.
The key function of DHH1 lies in its ability to bind and remodel RNA structures, facilitating or inhibiting the interaction of RNA with other molecules. This activity is central to the regulation of mRNA stability and translation. DHH1 can repress translation by binding to specific mRNA transcripts and either sequestering them in cytoplasmic granules known as P-bodies or directing them for degradation. This regulation ensures appropriate cellular responses to environmental changes and stress, contributing to the overall control of protein synthesis within the cell.DHH1's involvement in mRNA decay and translational repression makes it a pivotal player in various cellular processes, including stress response, cell cycle progression, and differentiation. Its activity is regulated by multiple factors, including interactions with other proteins and post-translational modifications, allowing for a fine-tuned response to internal and external cues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea induces replication stress, potentially enhancing DHH1 expression as part of the cellular stress response. | ||||||
Methyl methanesulfonate | 66-27-3 | sc-250376 sc-250376A | 5 g 25 g | $55.00 $130.00 | 2 | |
MMS, causing DNA damage, might upregulate DHH1 expression in response to genotoxic stress. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR signaling, potentially influencing DHH1 expression in response to nutrient deprivation. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin induces ER stress and might enhance DHH1 expression as part of the unfolded protein response. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine, influencing various cellular pathways, could potentially modulate DHH1 expression. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $106.00 $765.00 | 3 | |
Sodium arsenite induces oxidative stress, potentially influencing DHH1 expression as part of the cellular defense mechanism. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone, a glucocorticoid, might affect DHH1 expression in response to hormonal and stress signals. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin, inducing ER stress, could potentially enhance DHH1 expression in response to cellular stress. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin, by causing DNA damage, may trigger DHH1 expression in response to genotoxic stress. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide inhibits protein synthesis, potentially affecting DHH1 expression as part of a cellular stress response. | ||||||