DHDPSL Activators
DHDPSL Activators consist of a diverse array of biochemical compounds that influence the enzymatic activity of dihydrodipicolinate synthase ligase (DHDPSL). These activators can enhance the functional activity of DHDPSL through various mechanisms, such as providing substrates, cofactors, and allosteric regulators. Compounds like lysine, aspartic acid, and pyruvic acid serve as direct substrates for the DHDPSL-catalyzed reaction, facilitating the synthesis of dihydrodipicolinate, a precursor to lysine, and thus directly enhancing the functional activity of DHDPSL. The presence of these substrates in higher concentrations can lead to an increase in the catalytic efficiency of DHDPSL, effectively boosting its enzymatic throughput.
Alongside substrates, the activity of DHDPSL can be influenced by metabolites and cofactors such as ATP, NADH, NADPH, and acetyl-CoA. ATP is essential for the phosphorylation of compounds within the cell and can enhance DHDPSL activity indirectly by phosphorylating either DHDPSL itself or other proteins that interact with or regulate DHDPSL. NADH and NADPH are reducing agents that help maintain a proper redox state necessary for the optimal function of DHDPSL.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-Lysine | 56-87-1 | sc-207804 sc-207804A sc-207804B | 25 g 100 g 1 kg | $93.00 $258.00 $519.00 | ||
Lysine is a direct substrate for dihydrodipicolinate synthase (DHDPS), the first committed step in lysine biosynthesis. Elevated levels of lysine can enhance the activity of DHDPSL through feedback activation or substrate availability. | ||||||
L-Aspartic acid | 56-84-8 | sc-472377A sc-472377 sc-472377B | 25 g 100 g 500 g | $39.00 $32.00 $47.00 | ||
Aspartic acid functions as a precursor molecule in the dihydrodipicolinate synthase reaction catalyzed by DHDPSL, potentially increasing its enzymatic activity by providing substrate. | ||||||
Pyruvic acid | 127-17-3 | sc-208191 sc-208191A | 25 g 100 g | $40.00 $94.00 | ||
Pyruvate is involved in the condensation reaction with aspartic acid in the DHDPSL-mediated step in lysine biosynthesis, which could enhance DHDPSL activity by increasing substrate concentration. | ||||||
Magnesium chloride | 7786-30-3 | sc-255260C sc-255260B sc-255260 sc-255260A | 10 g 25 g 100 g 500 g | $27.00 $34.00 $47.00 $123.00 | 2 | |
Mg2+ ions are essential cofactors for the DHDPSL-catalyzed reaction, potentially enhancing its activity by stabilizing the enzyme-substrate complex. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
NADH is a cofactor that may interact with DHDPSL or its associated pathways, enhancing the reduction-oxidation reactions that could indirectly increase the activity of DHDPSL. | ||||||
β-Nicotinamide adenine dinucleotide phosphate | 53-59-8 | sc-215560 sc-215560A | 100 mg 250 mg | $114.00 $198.00 | ||
Similar to NADH, NADPH provides reducing power that can influence the enzymatic activity of DHDPSL by maintaining a favorable redox state. | ||||||
ADP | 58-64-0 | sc-507362 | 5 g | $53.00 | ||
ATP provides the phosphate group in many kinase reactions, which could indirectly enhance DHDPSL activity by phosphorylation of regulatory proteins within its pathway. | ||||||
Acetyl coenzyme A trisodium salt | 102029-73-2 | sc-210745 sc-210745A sc-210745B | 1 mg 5 mg 1 g | $46.00 $80.00 $5712.00 | 3 | |
Acetyl-CoA is a central metabolite that can donate acetyl groups, potentially enhancing the activity of DHDPSL through post-translational modifications of the enzyme or associated proteins. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $180.00 $655.00 | 2 | |
S-Adenosylmethionine serves as a methyl donor in numerous methylation reactions, which could enhance DHDPSL activity through methylation of the enzyme itself or regulatory proteins within its pathway. | ||||||
Fumaric acid | 110-17-8 | sc-250031 sc-250031A sc-250031B sc-250031C | 25 g 100 g 500 g 2.5 kg | $42.00 $56.00 $112.00 $224.00 | ||
Fumarate is part of the TCA cycle and can influence the metabolic flow, which could indirectly enhance DHDPSL activity by altering the availability of related substrates or cofactors. | ||||||