DENND4A Activators
DENND4A activators encompass a group of chemicals known to influence various cellular signaling pathways that can indirectly modulate the activity or functional relevance of DENND4A. For example, Forskolin, a known activator of adenylate cyclase, can raise cAMP levels, which may subsequently promote processes related to DENND4A. Similarly, substances like PMA activate protein kinase C, and such activation can touch upon pathways wherein DENND4A plays a role. Growth factors, such as EGF, trigger a multitude of intracellular cascades, and the broad influence of these cascades means they can indirectly modulate DENND4A functionality.
On the other hand, insulin's activation of the PI3K-AKT pathway presents another potential avenue for DENND4A modulation. Other chemicals like 8-Bromo-cAMP, which affects protein kinase A activity, is exemplary of how altering one pathway can ripple across interconnected cellular processes, potentially involving DENND4A. Given the intricate web of cell signaling, the modulation of kinases, phosphatases, or other pathway-specific molecules, as seen with compounds like Staurosporine or Rapamycin, offer potential indirect routes of DENND4A influence.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Can stimulate adenylate cyclase, increasing cAMP levels. Elevated cAMP might indirectly promote DENND4A-associated processes. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C (PKC). PKC activation may indirectly modulate DENND4A-associated pathways. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Activates the PI3K-AKT pathway, which might indirectly modulate the pathways in which DENND4A is involved. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
A cAMP analog that can modulate protein kinase A (PKA) activity, potentially affecting DENND4A-related pathways. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A sc-24000B sc-24000C | 10 µg 100 µg 500 µg 1 mg | $160.00 $750.00 $1400.00 $3000.00 | 59 | |
A protein phosphatase inhibitor which can elevate levels of phosphorylated proteins, potentially impacting DENND4A activity. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
Inhibits protein phosphatases, leading to increased phosphorylation states of proteins. This can indirectly influence pathways that DENND4A is involved in. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Calcium ionophore that can elevate intracellular calcium levels, potentially affecting DENND4A-associated cellular processes. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Broad-spectrum kinase inhibitor. By inhibiting multiple kinases, it can modulate various signaling pathways that may intersect with DENND4A functionality. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor. Modulating the mTOR pathway can indirectly influence the pathways and processes DENND4A is associated with. | ||||||