δ-Catenin Activators comprise a collection of chemicals that indirectly influence δ-Catenin function by modulating various cellular signaling pathways and mechanisms. δ-Catenin, integral to cell adhesion and neuronal synaptogenesis, interacts within a network of signaling pathways, making its modulation complex and multifaceted. Lithium Chloride, acting as a GSK-3β inhibitor, can stabilize β-catenin, indirectly influencing δ-catenin through related cell adhesion pathways. Valproic Acid, a histone deacetylase inhibitor, may alter gene expression patterns that intersect with δ-catenin's role in neural cells. Similarly, Trichostatin A, another histone deacetylase inhibitor, could impact δ-catenin function by modulating cellular signaling in neurons.
Compounds like Forskolin and Rolipram, which increase cAMP levels, may influence signaling pathways intersecting with δ-catenin's functions in synaptogenesis and cell adhesion. Epidermal Growth Factor (EGF) and Brain-Derived Neurotrophic Factor (BDNF), though not direct activators, modulate cell signaling pathways that can intersect with δ-catenin's roles. Retinoic Acid, involved in gene expression and neuronal differentiation, could also indirectly influence δ-catenin's function in neural development. Dibutyryl-cAMP, as a cell-permeable analog of cAMP, potentially modulates signaling pathways related to δ-catenin. Additionally, K252a, a kinase inhibitor, might impact neurotrophic factor signaling, affecting δ-catenin in neuronal cells. SB 431542 and PD98059, inhibitors of the TGF-beta receptor and MEK respectively, could influence signaling pathways related to δ-catenin in neuronal development and synapse formation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
A GSK-3β inhibitor that can stabilize β-catenin, which may indirectly influence δ-catenin through related cell adhesion and signaling pathways. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Acts as a histone deacetylase inhibitor, potentially affecting gene expression related to δ-catenin and its associated pathways in neural cells. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
An adenylyl cyclase activator that increases cAMP levels, potentially influencing signaling pathways that intersect with δ-catenin's role in neuronal function. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that can affect gene expression and might influence δ-catenin function indirectly by modulating cellular signaling in neurons. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
A phosphodiesterase inhibitor that increases cAMP, possibly influencing signaling pathways related to δ-catenin. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Involved in gene expression modulation and neuronal differentiation, it might indirectly influence δ-catenin's function in neural development. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
A cell-permeable cAMP analog that may modulate signaling pathways intersecting with δ-catenin’s role in synaptogenesis and cell adhesion. | ||||||
K-252a | 99533-80-9 | sc-200517 sc-200517B sc-200517A | 100 µg 500 µg 1 mg | $129.00 $214.00 $498.00 | 19 | |
A kinase inhibitor that may affect neurotrophic factor signaling, potentially impacting δ-catenin's role in neuronal cells. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
An inhibitor of the TGF-beta receptor, potentially affecting signaling pathways that intersect with δ-catenin function in neurons. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of MEK, which is part of the MAPK pathway, potentially influencing signaling pathways related to δ-catenin in neuronal development and synapse formation. | ||||||