Date published: 2025-9-10

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DDX26B Inibidores

DDX26B Inhibitors constitute a specific class of chemical compounds designed to selectively impede the activity of the DDX26B enzyme. DDX26B, also known as DEAD-box helicase 26B, belongs to the broader family of DEAD-box helicases, which are involved in RNA metabolism and contribute to various aspects of RNA processing, including transcription, splicing, and translation. The development of inhibitors targeting DDX26B is pivotal for scientific exploration, offering specialized tools to elucidate the molecular functions and regulatory roles associated with this particular helicase. As a member of the DEAD-box helicase family, DDX26B likely plays a role in unwinding RNA secondary structures, facilitating RNA-protein interactions, and modulating the dynamic landscape of cellular RNA processing events.

The synthesis and optimization of DDX26B inhibitors necessitate a thorough understanding of the enzyme's structural features and its interactions within cellular pathways. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of DDX26B and interfere with its normal helicase activities. By utilizing DDX26B inhibitors in experimental settings, researchers can investigate the consequences of enzyme inhibition on RNA processing dynamics, shedding light on the specific substrates and molecular pathways governed by DDX26B. The study of DDX26B inhibitors contributes to the broader comprehension of cellular RNA metabolism, providing insights into the intricate molecular mechanisms that regulate gene expression and RNA-related processes in cells.

VEJA TAMBÉM

Nome do ProdutoCAS #Numero de CatalogoQuantidadePrecoUso e aplicacaoNOTAS

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

A actinomicina D liga-se ao ADN, inibindo a transcrição e impedindo a síntese do ARNm do DDX26B.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

A ciclo-heximida interrompe a síntese proteica, levando a uma redução da expressão de DDX26B através da inibição da tradução.

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
$40.00
$210.00
$816.00
$65.00
394
(15)

A puromicina induz a terminação prematura da síntese proteica, afectando a tradução e diminuindo os níveis de DDX26B.

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$95.00
$322.00
$663.00
$1438.00
6
(1)

A rifampicina inibe a RNA polimerase bacteriana, suprimindo indiretamente a expressão de DDX26B ao interferir com a transcrição.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

A anisomicina dificulta a síntese proteica ao bloquear a atividade da peptidil transferase, conduzindo a uma síntese reduzida de DDX26B.

Cordycepin

73-03-0sc-203902
10 mg
$99.00
5
(1)

A cordicepina interfere com a síntese de ARNm, afectando a transcrição e contribuindo para a regulação negativa do DDX26B.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$68.00
$261.00
8
(1)

O ácido micofenólico inibe a inosina monofosfato desidrogenase, afectando indiretamente a expressão de DDX26B ao perturbar a síntese de purinas.

Blasticidin S Hydrochloride

3513-03-9sc-204655A
sc-204655
25 mg
100 mg
$360.00
$475.00
20
(2)

A blasticidina S induz a terminação prematura durante a tradução, inibindo a síntese proteica e reduzindo os níveis de DDX26B.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$36.00
$149.00
11
(1)

O 5-Fluorouracil interfere com a síntese de ARN, afectando a expressão de DDX26B ao interromper a produção de ARNm.