D230039L06Rik Inhibitors
Kif26b, a member of the kinesin family, is predicted to play a crucial role in microtubule binding and motor activities. It is associated with cellular processes such as the establishment of cell polarity, positive regulation of cell-cell adhesion, and ureteric bud invasion, all of which are vital for normal cellular development and function. Located in the cytoplasm and cytoskeleton, Kif26b is expressed in various structures, including the alimentary system, central nervous system, genitourinary system, hindlimb interdigital region, and sensory organs.
Inhibition of Kif26b involves targeting its predicted microtubule-related functions. Chemicals like Nocodazole, Colchicine, Paclitaxel, Vinblastine, Griseofulvin, Vincristine, Vinorelbine, Epothilone B, Thiabendazole, Vinflunine, Podophyllotoxin, and Combretastatin A4 act either directly or indirectly on microtubule dynamics, influencing Kif26b's role in cellular processes. For instance, destabilizing agents like Nocodazole and Vinblastine disrupt microtubule structure, potentially impacting Kif26b's involvement in the establishment of cell polarity and cell-cell adhesion. Stabilizing agents like Paclitaxel and Epothilone B alter microtubule stability, potentially influencing Kif26b's role in the same processes. The diverse mechanisms of inhibition highlight the importance of microtubule dynamics in regulating Kif26b's functions and provide insights into potential strategies for modulating its activity in cellular contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubule dynamics by inhibiting polymerization. Kif26b, predicted to have microtubule motor activity, may be indirectly inhibited by Nocodazole through disruption of microtubule structure, affecting Kif26b's role in microtubule-based cellular processes such as cell polarity and cell-cell adhesion. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Colchicine inhibits microtubule polymerization, impacting microtubule stability. Kif26b, with predicted microtubule binding activity, may be indirectly influenced by Colchicine through disruption of microtubule dynamics, affecting Kif26b's involvement in cellular processes related to microtubule functions. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Taxol stabilizes microtubules, affecting microtubule dynamics. Kif26b, with predicted microtubule binding and motor activity, may be indirectly impacted by Paclitaxel through alteration of microtubule stability, influencing Kif26b's role in cellular processes such as cell polarity and cell-cell adhesion. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Vinblastine disrupts microtubule dynamics by inhibiting polymerization. Kif26b, predicted to have microtubule motor activity, may be indirectly inhibited by Vinblastine through disruption of microtubule structure, affecting Kif26b's involvement in microtubule-dependent cellular processes like cell polarity and cell-cell adhesion. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $85.00 $220.00 $598.00 | 4 | |
Griseofulvin inhibits microtubule polymerization, impacting microtubule stability. Kif26b, with predicted microtubule binding activity, may be indirectly influenced by Griseofulvin through disturbance of microtubule dynamics, affecting Kif26b's role in cellular processes associated with microtubules, such as establishment of cell polarity. | ||||||
Vinorelbine base | 71486-22-1 | sc-205885 sc-205885A sc-205885B sc-205885C sc-205885D | 1 mg 5 mg 25 mg 100 mg 1 g | $29.00 $81.00 $260.00 $791.00 $1977.00 | ||
Vinorelbine disrupts microtubule dynamics by inhibiting polymerization. Kif26b, with predicted microtubule binding activity, may be indirectly influenced by Vinorelbine through disruption of microtubule structure, affecting Kif26b's role in cellular processes associated with microtubules, such as establishment of cell polarity. | ||||||
Epothilone B, Synthetic | 152044-54-7 | sc-203944 | 2 mg | $176.00 | ||
Epothilone B stabilizes microtubules, impacting microtubule dynamics. Kif26b, predicted to have microtubule binding and motor activity, may be indirectly impacted by Epothilone B through alteration of microtubule stability, influencing Kif26b's involvement in cellular processes such as cell polarity and cell-cell adhesion. | ||||||
Thiabendazole | 148-79-8 | sc-204913 sc-204913A sc-204913B sc-204913C sc-204913D | 10 g 100 g 250 g 500 g 1 kg | $32.00 $84.00 $183.00 $312.00 $572.00 | 5 | |
Thiabendazole inhibits microtubule polymerization, affecting microtubule stability. Kif26b, with predicted microtubule binding activity, may be indirectly influenced by Thiabendazole through disturbance of microtubule dynamics, affecting Kif26b's role in cellular processes related to microtubules, such as establishment of cell polarity. | ||||||
Vinflunine | 162652-95-1 | sc-507411 | 10 mg | $390.00 | ||
Vinflunine disrupts microtubule dynamics by inhibiting polymerization. Kif26b, predicted to have microtubule motor activity, may be indirectly inhibited by Vinflunine through interference with microtubule structure, impacting Kif26b's involvement in cellular processes associated with microtubules, such as establishment of cell polarity. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $84.00 | 1 | |
Podophyllotoxin inhibits microtubule polymerization, affecting microtubule stability. Kif26b, with predicted microtubule binding activity, may be indirectly influenced by Podophyllotoxin through disturbance of microtubule dynamics, affecting Kif26b's role in cellular processes related to microtubules, such as establishment of cell polarity. | ||||||