Vinflunine (CAS 162652-95-1)
Alternate Names:
20′,20′-difluoro-3′,4′-dihydrovinorelbine CHEBI:90241 4′-Deoxy-20′,20′-difluoro-C′-norvincaleukoblastine
CAS Number:
162652-95-1
Molecular Weight:
816.90
Molecular Formula:
C45H54F2N4O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Vinflunine (CAS 162652-95-1) References
- Vinflunine, the latest Vinca alkaloid in clinical development. A review of its preclinical anticancer properties. | Kruczynski, A. and Hill, BT. 2001. Crit Rev Oncol Hematol. 40: 159-73. PMID: 11682323
- Vinflunine: a new microtubule inhibitor agent. | Bennouna, J., et al. 2008. Clin Cancer Res. 14: 1625-32. PMID: 18347163
- Vinflunine in the treatment of advanced bladder cancer. | Mamtani, R. and Vaughn, DJ. 2011. Expert Rev Anticancer Ther. 11: 13-20. PMID: 21166506
- Vinflunine: a fluorinated vinca alkaloid for bladder cancer therapy. | Gerullis, H. 2011. Drugs Today (Barc). 47: 17-25. PMID: 21373647
- Vinflunine: drug safety evaluation of this novel synthetic vinca alkaloid. | Schutz, FA., et al. 2011. Expert Opin Drug Saf. 10: 645-53. PMID: 21524237
- Vinflunine for the treatment of breast cancer. | Gourmelon, C., et al. 2016. Expert Opin Pharmacother. 17: 1817-23. PMID: 27484180
- Vinflunine for the treatment of non-small cell lung cancer. | Genova, C., et al. 2016. Expert Opin Investig Drugs. 25: 1447-1455. PMID: 27771969
- Vinflunine in the treatment of advanced urothelial cancer: clinical evidence and experience. | Gerullis, H., et al. 2017. Ther Adv Urol. 9: 28-35. PMID: 28042310
- Randomized phase III KEYNOTE-045 trial of pembrolizumab versus paclitaxel, docetaxel, or vinflunine in recurrent advanced urothelial cancer: results of >2 years of follow-up. | Fradet, Y., et al. 2019. Ann Oncol. 30: 970-976. PMID: 31050707
- Enfortumab Vedotin in Previously Treated Advanced Urothelial Carcinoma. | Powles, T., et al. 2021. N Engl J Med. 384: 1125-1135. PMID: 33577729
Inhibitor of:
β3 Tubulin, β5 Tubulin, 1700019B03Rik, CCDC61, D230039L06Rik, EG546143, periphilin 1, TBCB, TBCC, TBCCD1, Tctex2 β, and TTLL7.Activator of:
γ Tubulin, and HAGHL.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vinflunine, 10 mg | sc-507411 | 10 mg | $390.00 |