D14Ertd668e Activators
Phf11d, a metal ion binding protein located in the nuclear membrane and nucleoplasm, plays a crucial role in cellular processes within these compartments. Predicted to enable metal ion binding activity, Phf11d is expressed in various tissues, including the alimentary system and axial musculature. Activation of Phf11d involves a sophisticated interplay with various chemical activators targeting different cellular processes.
Chemicals like Vorinostat and Sodium Butyrate act as direct activators by inhibiting histone deacetylases and promoting histone acetylation, respectively. These actions create an environment conducive to the metal ion binding activity of Phf11d in the nuclear membrane. Compounds like JQ1 and Curcumin stimulate Phf11d through bromodomain inhibition and NF-κB pathway modulation, respectively, impacting nucleoplasmic processes crucial for metal ion binding. Indirect activators like 5-Azacytidine and Betaine alter DNA methylation patterns and cellular methylation, respectively, creating conditions favorable for Phf11d function. In conclusion, the orchestrated activation of Phf11d by these diverse chemicals underscores the intricate regulatory mechanisms governing its metal ion binding activity in the nuclear membrane and nucleoplasm, revealing potential avenues for manipulating cellular processes associated with these compartments.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Activates Phf11d by inhibiting histone deacetylases, promoting an environment conducive to its function in the nuclear membrane and nucleoplasm. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Enhances Phf11d activity by promoting histone acetylation, facilitating metal ion binding in the nuclear membrane. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
Stimulates Phf11d through bromodomain inhibition, influencing nucleoplasmic processes and metal ion binding activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Upregulates Phf11d by modulating the NF-κB pathway, impacting the expression of factors crucial for metal ion binding in the nuclear membrane. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Acts as a Phf11d stimulator by modulating NAD+ levels, impacting sirtuin-mediated processes involved in metal ion binding in the nuclear membrane. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Activates Phf11d through histone deacetylase inhibition, promoting an environment conducive to its metal ion binding activity in the nuclear membrane. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Stimulates Phf11d through activation of SIRT1, leading to increased metal ion binding activity in the nuclear membrane. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $30.00 $40.00 $55.00 $160.00 $330.00 $580.00 | 2 | |
Enhances Phf11d activity by influencing cellular methylation patterns, contributing to optimal metal ion binding in the nuclear membrane. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Indirectly activates Phf11d by altering DNA methylation patterns, creating conditions favorable for metal ion binding in the nuclear membrane. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Upregulates Phf11d through antioxidant mechanisms, impacting cellular redox status and creating conditions favorable for metal ion binding in the nuclear membrane. | ||||||