Cytokeratin 2p Activators
Cytokeratin 2p Activators is a class of compounds that can induce the activation of Cytokeratin 2p, either directly or indirectly. These chemicals act by modulating different biochemical pathways that are essential for the function and regulation of keratins in general and Cytokeratin 2p in particular. This class of activators includes various types of compounds, such as retinoids, glucocorticoids, growth factors, and others.
Retinoids like all-trans retinoic acid, and calcitriol, the active form of vitamin D, can induce the differentiation of epithelial cells, leading to an upregulation of keratin expression. This category also includes glucocorticoids like dexamethasone, which can stimulate the expression of keratins in epithelial cells and growth factors like EGF, which can trigger signaling pathways leading to keratinocyte proliferation and differentiation. Further, compounds like caffeine and forskolin are included that can modulate cyclic AMP levels, influencing keratin expression in epithelial cells. Other compounds like PMA, sulforaphane, betulinic acid, lithium chloride, aloe-emodin, and ascorbic acid act on different pathways and cellular processes, leading to changes in keratin expression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
All-trans retinoic acid can induce differentiation and upregulation of keratin expression in epithelial cells, potentially leading to an increase in Cytokeratin 2p expression. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $220.00 $645.00 $1000.00 $1500.00 $440.00 | 32 | |
Calcitriol, the active form of vitamin D, can stimulate keratinocyte differentiation, possibly enhancing Cytokeratin 2p activation. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a glucocorticoid, can stimulate the expression of keratins in epithelial cells, which might lead to Cytokeratin 2p activation. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine can modulate cyclic AMP levels, which can influence keratin expression in epithelial cells, potentially activating Cytokeratin 2p. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin can elevate cyclic AMP levels, thus potentially upregulating keratin expression, including that of Cytokeratin 2p. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA can activate protein kinase C, leading to changes in keratin expression in epithelial cells and possible activation of Cytokeratin 2p. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane can induce phase II detoxification enzymes, leading to changes in the redox state of the cell, which can indirectly influence keratin expression and potentially activate Cytokeratin 2p. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
Betulinic Acid can induce apoptosis in keratinocytes, leading to compensatory proliferation and a possible increase in Cytokeratin 2p expression. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can inhibit glycogen synthase kinase-3 beta, leading to changes in keratin expression and potential activation of Cytokeratin 2p. | ||||||
Emodin | 518-82-1 | sc-202601 sc-202601A sc-202601B | 50 mg 250 mg 15 g | $105.00 $214.00 $6255.00 | 2 | |
Aloe-emodin can affect keratinocyte proliferation and differentiation, potentially influencing Cytokeratin 2p. | ||||||