CYP4A32 is a member of the cytochrome P450 family, a diverse group of enzymes known for their role in metabolizing a wide range of substrates, including drugs, toxins, and endogenous compounds like steroids and fatty acids. The cytochrome P450 enzymes are heme-thiolate proteins, meaning they contain a heme (iron-containing) group and use a sulfur-containing cysteine residue to bind to the heme and oxygen. These enzymes are primarily found in the liver, where they play a critical role in detoxifying substances.The specific role and characteristics of CYP4A32, like many cytochrome P450 enzymes, are likely centered around the metabolism of fatty acids. This is deduced from the general function of the CYP4 family, which is predominantly involved in the hydroxylation of fatty acids – a process essential for breaking down these molecules for energy or converting them into other useful forms.
CYP4A32's activity suggests it could be significant in physiological processes like energy homeostasis, the regulation of lipid levels, and possibly in the response to certain drugs or environmental chemicals. The expression of CYP4A32 might be influenced by various factors including dietary components, hormonal levels, and exposure to certain drugs or toxicants.Understanding the specific substrates and regulatory mechanisms of CYP4A32 is crucial for insights into its role in metabolism and implications in disorders related to lipid metabolism, liver function, and the body's response to certain drugs and environmental agents.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Clofibrate | 637-07-0 | sc-200721 | 1 g | $33.00 | ||
Clofibrate, a lipid-lowering agent, may induce CYP4A32 as part of a mechanism to regulate lipid metabolism. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $41.00 | 9 | |
Fenofibrate, used to reduce cholesterol levels, may upregulate CYP4A32 as it modulates lipid processing in the liver. | ||||||
Gemfibrozil | 25812-30-0 | sc-204764 sc-204764A | 5 g 25 g | $66.00 $267.00 | 2 | |
Gemfibrozil, another lipid-regulating agent, might stimulate CYP4A32 expression to enhance fatty acid metabolism. | ||||||
WY 14643 | 50892-23-4 | sc-203314 | 50 mg | $136.00 | 7 | |
WY-14643, a PPAR-alpha agonist, potentially enhances CYP4A32 expression through PPAR-mediated pathways. | ||||||
Bis(2-ethylhexyl) phthalate | 117-81-7 | sc-254975 | 1 g | $57.00 | 2 | |
Phthalates, particularly di-2-ethylhexyl phthalate (DEHP), might induce CYP4A32 as they interfere with lipid metabolism. | ||||||
3-Methylcholanthrene | 56-49-5 | sc-252030 sc-252030A | 100 mg 250 mg | $388.00 $831.00 | 2 | |
This compound may increase CYP4A32 expression as a response to its role in xenobiotic metabolism. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid, a derivative of Vitamin A, might modulate CYP4A32 expression through its role in cellular signaling. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
As a glucocorticoid, Dexamethasone could influence CYP4A32 expression through glucocorticoid-responsive elements. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
Rifampicin, an antibiotic, may induce CYP4A32 as it is known to affect the expression of various cytochrome P450 enzymes. | ||||||