cyclin M1 Activators
Cyclin M1 Activators are chemicals that can enhance the functional activity of cyclin M1 through specific signaling pathways that cyclin M1 is directly involved in. All the chemicals listed here either directly or indirectly alter intracellular ion concentrations, which can affect the function of cyclin M1, a known metal ion transporter. Chemicals like Furosemide, Chloroquine, and Bafilomycin A1 are known to alter intracellular ion concentrations through various mechanisms. Furosemide inhibits the Na-K-2Cl symporter in the thick ascending limb of the loop of Henle. Both Chloroquine and Bafilomycin A1 alter intracellular pH and ion concentrations, with Chloroquine being a weak base that accumulates in acidic vesicles, and Bafilomycin A1 specifically inhibiting vacuolar-type H+-ATPases.
On the other hand, Zinc Pyrithione, Nigericin, Monensin, Valinomycin, EGTA, and EDTA directly or indirectly affect cyclin M1 by altering intracellular concentrations of certain specific ions. For instance, Zinc Pyrithione enhances the transport of Zn2+ ions across cell membranes, while Nigericin, Monensin, and Valinomycin are ionophores that alter intracellular potassium and sodium concentrations. EGTA and EDTA are chelating agents that bind to metal ions, thereby altering their intracellular concentrations.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Furosemide | 54-31-9 | sc-203961 | 50 mg | $40.00 | ||
Furosemide, a loop diuretic, inhibits the Na-K-2Cl symporter in the thick ascending limb of the loop of Henle. This can influence intracellular ion concentrations, indirectly affecting cyclin M1 function. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc Pyrithione is a zinc ionophore, enhancing the transport of Zn2+ ions across cell membranes. This can influence cyclin M1, which is involved in zinc transport. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine is a weak base that accumulates in acidic vesicles, influencing intracellular pH and ion concentrations. This may indirectly affect the function of cyclin M1, given its role in metal ion transport. | ||||||
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
Bafilomycin A1 is a specific inhibitor of vacuolar-type H+-ATPases. By altering intracellular pH and ion concentrations, it could indirectly influence cyclin M1 activity. | ||||||
Nigericin sodium salt | 28643-80-3 | sc-201518A sc-201518 sc-201518B sc-201518C sc-201518D | 1 mg 5 mg 25 mg 1 g 5 g | $45.00 $110.00 $235.00 $6940.00 $26879.00 | 9 | |
Nigericin is a potassium ionophore that alters intracellular potassium concentrations. This can indirectly influence the activity of cyclin M1, a metal ion transporter. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $152.00 $515.00 | ||
Monensin is a sodium ionophore that alters intracellular sodium concentrations. This can indirectly influence the activity of cyclin M1, a metal ion transporter. | ||||||
Valinomycin | 2001-95-8 | sc-200991 | 25 mg | $163.00 | 3 | |
Valinomycin is a potassium ionophore that alters intracellular potassium concentrations. This can indirectly influence the activity of cyclin M1, a metal ion transporter. | ||||||
EGTA | 67-42-5 | sc-3593 sc-3593A sc-3593B sc-3593C sc-3593D | 1 g 10 g 100 g 250 g 1 kg | $20.00 $62.00 $116.00 $246.00 $799.00 | 23 | |
EGTA is a chelating agent that strongly binds to calcium ions, altering intracellular calcium concentrations. This can indirectly influence the function of cyclin M1, which is involved in metal ion transport. | ||||||