CXorf57_D330045A20Rik Inhibitors
The chemical class referred to as CXorf57_D330045A20Rik Inhibitors constitutes a group of compounds that can influence the function or activity of the RPA1 related single-stranded DNA binding protein, X-linked. These compounds are not specific inhibitors of CXorf57_D330045A20Rik but are selected based on their known effects on cellular processes related to DNA replication, repair, and the cellular stress response. The inhibitory actions of these chemicals are indirect and operate by altering the cellular environment or by targeting proteins that interact with or modify the activity of DNA-binding proteins like CXorf57_D330045A20Rik.
The selected chemicals can influence the function of CXorf57_D330045A20Rik by various mechanisms such as causing DNA damage that necessitates the involvement of DNA repair machinery, depleting nucleotide pools thus affecting DNA synthesis, or inhibiting key enzymes that initiate responses to DNA damage. Their actions may impact the stability, localization, or interaction of CXorf57_D330045A20Rik with single-stranded DNA or other proteins involved in DNA metabolism. In this context, the compounds listed can be considered as indirect modulators of the protein's activity, with the potential to affect its normal function within the cell. These compounds are diverse in structure and biological activity, but all share the common feature of interacting with DNA or influencing pathways that are crucial for maintaining DNA integrity during cellular processes such as replication and repair.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Interfers with DNA replication by inhibiting Topoisomerase I, which may indirectly affect the binding activity of single-stranded DNA binding proteins. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Inhibits ribonucleotide reductase, decreasing deoxyribonucleotide pools and affecting DNA synthesis and repair, potentially altering the function of DNA binding proteins. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Targets Topoisomerase II, leading to DNA damage and potentially disrupting the interaction of DNA binding proteins with replication forks. | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $82.00 $300.00 $1082.00 | 30 | |
Blocks DNA polymerase, which can cause replication stress and may impact the function of proteins involved in DNA replication. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
Forms DNA crosslinks that impede replication and transcription, potentially affecting proteins that stabilize single-stranded DNA. | ||||||
2′-Deoxy-2′,2′-difluorocytidine | 95058-81-4 | sc-275523 sc-275523A | 1 g 5 g | $56.00 $128.00 | ||
Nucleoside analog that incorporates into DNA and inhibits elongation, possibly altering the dynamics of DNA binding proteins. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Generates DNA crosslinks, similarly to Cisplatin, and can disrupt processes requiring single-stranded DNA stabilization. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Interacts with DNA at the transcription initiation complex, affecting transcription and potentially influencing DNA binding proteins. | ||||||
VE 821 | 1232410-49-9 | sc-475878 | 10 mg | $360.00 | ||
Inhibits the ATR kinase that is activated during DNA replication stress, which might indirectly affect single-stranded DNA binding proteins. | ||||||
AZD7762 | 860352-01-8 | sc-364423 | 2 mg | $107.00 | ||
Inhibits CHK1, a kinase involved in DNA damage response, potentially impacting the function of proteins associated with DNA repair. | ||||||