CTAGE9 Inhibitors
CTAGE9 inhibitors are a class of chemicals that can potentially inhibit the function of the CTAGE9 protein. CTAGE9, also known as Cutaneous T-cell lymphoma-associated antigen 9, is a protein involved in intracellular trafficking, vesicular transport, and pH regulation. The inhibitors of CTAGE9 can act through various mechanisms to disrupt its function. Bafilomycin A1 and Concanamycin A, for example, inhibit CTAGE9 by inhibiting the vacuolar-type H+-ATPase (V-ATPase), which is essential for intracellular trafficking and vesicle formation. Thisinhibition can disrupt CTAGE9-mediated processes. EIPA and N-ethylmaleimide can inhibit CTAGE9 by disrupting ion transport and pH regulation. EIPA is a selective inhibitor of the Na+/H+ exchanger (NHE), while N-ethylmaleimide modifies cysteine residues and disrupts protein-protein interactions essential for CTAGE9 function.
Wortmannin inhibits CTAGE9 by inhibiting phosphoinositide 3-kinase (PI3K), a signaling enzyme involved in intracellular trafficking and vesicle formation. Dynamin Inhibitor I, Dynasore and Pitstop 2 inhibit CTAGE9 by inhibiting dynamin and disrupting clathrin-mediated endocytosis, respectively. These processes are crucial for intracellular trafficking and vesicular transport. Chlorpromazine, Nystatin, Streptomyces noursei, Methyl-β-cyclodextrin, Cytochalasin D, and Latrunculin B, Latrunculia magnifica can inhibit CTAGE9 by disrupting membrane integrity, lipid organization, and actin polymerization, which are all involved in intracellular transport and vesicle formation. Overall, CTAGE9 inhibitors target various cellular processes involved in intracellular trafficking, vesicular transport, ion transport, pH regulation, and protein-protein interactions. By disrupting these processes, these inhibitors can potentially inhibit the function of CTAGE9 and its associated cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $98.00 $255.00 $765.00 $1457.00 | 280 | |
Bafilomycin A1 is a macrolide antibiotic that can potentially inhibit CTAGE9 by inhibiting the vacuolar-type H+-ATPase (V-ATPase), which is involved in intracellular trafficking and vesicular transport. This can lead to the inhibition of CTAGE9-mediated processes. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a fungal metabolite that can potentially inhibit CTAGE9 by inhibiting phosphoinositide 3-kinase (PI3K), a signaling enzyme involved in intracellular trafficking and vesicle formation. This can lead to the inhibition of CTAGE9-mediated processes. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Dynamin Inhibitor I, Dynasore is a small molecule inhibitor that can potentially inhibit CTAGE9 by inhibiting dynamin, a GTPase involved in endocytosis and vesicle formation. This can lead to the inhibition of CTAGE9-mediated processes. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Chlorpromazine is an antipsychotic compound that can potentially inhibit CTAGE9 by disrupting clathrin-mediated endocytosis, which is involved in intracellular trafficking and vesicular transport. This can lead to the inhibition of CTAGE9 function. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $69.00 $214.00 $796.00 $1918.00 | 19 | |
N-ethylmaleimide is a thiol-reactive compound that can potentially inhibit CTAGE9 by modifying cysteine residues and disrupting protein-protein interactions essential for CTAGE9-mediated processes. | ||||||
Methyl-β-cyclodextrin | 128446-36-6 | sc-215379A sc-215379 sc-215379C sc-215379B | 100 mg 1 g 10 g 5 g | $20.00 $48.00 $160.00 $82.00 | 19 | |
Methyl-β-cyclodextrin is a cyclic oligosaccharide that can potentially inhibit CTAGE9 by disrupting lipid rafts, which are involved in intracellular trafficking and vesicle formation. This can lead to the inhibition of CTAGE9 function. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D is a fungal metabolite that can potentially inhibit CTAGE9 by disrupting actin polymerization, which is involved in intracellular transport and vesicle formation. This can lead to the inhibition of CTAGE9-mediated processes. | ||||||
Nystatin | 1400-61-9 | sc-212431 sc-212431A sc-212431B sc-212431C | 5 MU 25 MU 250 MU 5000 MU | $51.00 $129.00 $251.00 $3570.00 | 7 | |
Nystatin, Streptomyces noursei is an antifungal compound that can potentially inhibit CTAGE9 by disrupting membrane integrity and lipid organization, which are essential for CTAGE9-mediated processes. This can lead to the inhibition of CTAGE9 function. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Latrunculin B, Latrunculia magnifica is a marine toxin that can potentially inhibit CTAGE9 by disrupting actin polymerization, which is involved in intracellular transport and vesicle formation. This can lead to the inhibition of CTAGE9-mediated processes. | ||||||
Pitstop 2 | 1419320-73-2 | sc-507418 | 10 mg | $360.00 | ||
Pitstop 2 is a small molecule inhibitor that can potentially inhibit CTAGE9 by disrupting clathrin-mediated endocytosis, which is involved in intracellular trafficking and vesicular transport. This can lead to the inhibition of CTAGE9 function. | ||||||