CRS1C-2, with its predicted function in protein homodimerization and involvement in various immune responses, plays a pivotal role in antimicrobial defense, particularly in mucosal tissues. Activation of CRS1C-2 is orchestrated by a range of chemicals that act as direct or indirect activators, influencing key pathways and processes in the innate immune response. Poly(I:C) and CpG Oligodeoxynucleotides mimic microbial components, triggering CRS1C-2 activation and enhancing antimicrobial humoral immune responses, providing a rapid defense against microbial threats. Specialized pro-resolving mediator Resolvin D1 and polyphenolic compounds like Quercetin and Curcumin contribute to resolving inflammation and amplifying antimicrobial immune responses in mucosal tissues.
Compounds such as Lactoferrin, Beta-Glucans, N-Acetylcysteine (NAC), and Zinc play roles in supporting antimicrobial humoral immune responses, fortifying mucosal defenses against bacterial challenges. Additionally, omega-3 fatty acids and Vitamin D contribute to modulating immune responses and amplifying innate immune reactions against microbial threats. In summary, the activation of CRS1C-2 involves a sophisticated interplay of various chemicals that collectively bolster the antimicrobial humoral immune responses, particularly in mucosal tissues. Understanding these activation mechanisms provides insights into potential strategies for enhancing the innate immune response against bacterial challenges, shedding light on the intricate dynamics of host defense mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | $139.00 $663.00 | 2 | |
Poly(I:C) activates CRS1C-2 by mimicking viral RNA, triggering an innate immune response. This enhances antimicrobial humoral immune response, particularly mediated by antimicrobial peptides, contributing to an effective defense against microbial threats. | ||||||
Resolvin D1 | 872993-05-0 | sc-204877 sc-204877A | 10 µg 25 µg | $262.00 $614.00 | 1 | |
Resolvin D1 activates CRS1C-2 by resolving inflammation and promoting an antimicrobial humoral immune response. This specialized pro-resolving mediator enhances mucosal immune responses, playing a crucial role in the innate defense against bacterial threats. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin activates CRS1C-2 by modulating immune signaling pathways, enhancing antimicrobial humoral immune responses. This flavonoid strengthens mucosal immune defenses, providing a potential avenue to fortify the innate immune response against bacterial challenges. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin activates CRS1C-2 by modulating immune signaling, amplifying antimicrobial humoral immune responses. This polyphenol supports mucosal immune defenses, offering a potential strategy to bolster the innate immune response against bacterial threats. | ||||||
Lactoferrin | 146897-68-9 | sc-394420 sc-394420A sc-394420B sc-394420C | 10 mg 50 mg 100 mg 1 g | $122.00 $408.00 $580.00 $1494.00 | ||
Lactoferrin activates CRS1C-2 by promoting antimicrobial humoral immune responses, particularly in mucosal tissues. This multifunctional glycoprotein supports innate immune defenses, contributing to the effective recognition and response to bacterial challenges. | ||||||
b-Glucan, Saccharomyces cerevisiae | 9012-72-0 | sc-203832 | 25 mg | $307.00 | ||
Beta-Glucans activate CRS1C-2 by engaging immune receptors, enhancing antimicrobial humoral immune responses. These polysaccharides strengthen mucosal immune defenses, providing a potential avenue to amplify the innate immune response against bacterial challenges. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
N-Acetylcysteine activates CRS1C-2 by modulating oxidative stress, supporting antimicrobial humoral immune responses. This antioxidant reinforces mucosal immune defenses, offering a potential strategy to enhance the innate immune response against bacterial threats. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc activates CRS1C-2 by influencing immune signaling, promoting antimicrobial humoral immune responses. This essential trace element supports mucosal immune defenses, providing a potential avenue to fortify the innate immune response against bacterial challenges. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Cholecalciferol activates CRS1C-2 by modulating immune responses, enhancing antimicrobial humoral immune reactions. This fat-soluble vitamin supports mucosal immune defenses, offering potential strategies to amplify the innate immune response against bacterial threats. | ||||||