Date published: 2026-6-13

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CRS1C-2 Activators

CRS1C-2, with its predicted function in protein homodimerization and involvement in various immune responses, plays a pivotal role in antimicrobial defense, particularly in mucosal tissues. Activation of CRS1C-2 is orchestrated by a range of chemicals that act as direct or indirect activators, influencing key pathways and processes in the innate immune response. Poly(I:C) and CpG Oligodeoxynucleotides mimic microbial components, triggering CRS1C-2 activation and enhancing antimicrobial humoral immune responses, providing a rapid defense against microbial threats. Specialized pro-resolving mediator Resolvin D1 and polyphenolic compounds like Quercetin and Curcumin contribute to resolving inflammation and amplifying antimicrobial immune responses in mucosal tissues.

Compounds such as Lactoferrin, Beta-Glucans, N-Acetylcysteine (NAC), and Zinc play roles in supporting antimicrobial humoral immune responses, fortifying mucosal defenses against bacterial challenges. Additionally, omega-3 fatty acids and Vitamin D contribute to modulating immune responses and amplifying innate immune reactions against microbial threats. In summary, the activation of CRS1C-2 involves a sophisticated interplay of various chemicals that collectively bolster the antimicrobial humoral immune responses, particularly in mucosal tissues. Understanding these activation mechanisms provides insights into potential strategies for enhancing the innate immune response against bacterial challenges, shedding light on the intricate dynamics of host defense mechanisms.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Polyinosinic acid - polycytidylic acid sodium salt, double-stranded

42424-50-0sc-204854
sc-204854A
10 mg
100 mg
$139.00
$663.00
2
(1)

Poly(I:C) activates CRS1C-2 by mimicking viral RNA, triggering an innate immune response. This enhances antimicrobial humoral immune response, particularly mediated by antimicrobial peptides, contributing to an effective defense against microbial threats.

Resolvin D1

872993-05-0sc-204877
sc-204877A
10 µg
25 µg
$262.00
$614.00
1
(1)

Resolvin D1 activates CRS1C-2 by resolving inflammation and promoting an antimicrobial humoral immune response. This specialized pro-resolving mediator enhances mucosal immune responses, playing a crucial role in the innate defense against bacterial threats.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin activates CRS1C-2 by modulating immune signaling pathways, enhancing antimicrobial humoral immune responses. This flavonoid strengthens mucosal immune defenses, providing a potential avenue to fortify the innate immune response against bacterial challenges.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin activates CRS1C-2 by modulating immune signaling, amplifying antimicrobial humoral immune responses. This polyphenol supports mucosal immune defenses, offering a potential strategy to bolster the innate immune response against bacterial threats.

Lactoferrin

146897-68-9sc-394420
sc-394420A
sc-394420B
sc-394420C
10 mg
50 mg
100 mg
1 g
$122.00
$408.00
$580.00
$1494.00
(1)

Lactoferrin activates CRS1C-2 by promoting antimicrobial humoral immune responses, particularly in mucosal tissues. This multifunctional glycoprotein supports innate immune defenses, contributing to the effective recognition and response to bacterial challenges.

b-Glucan, Saccharomyces cerevisiae

9012-72-0sc-203832
25 mg
$307.00
(0)

Beta-Glucans activate CRS1C-2 by engaging immune receptors, enhancing antimicrobial humoral immune responses. These polysaccharides strengthen mucosal immune defenses, providing a potential avenue to amplify the innate immune response against bacterial challenges.

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$34.00
$74.00
$270.00
$114.00
34
(1)

N-Acetylcysteine activates CRS1C-2 by modulating oxidative stress, supporting antimicrobial humoral immune responses. This antioxidant reinforces mucosal immune defenses, offering a potential strategy to enhance the innate immune response against bacterial threats.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

Zinc activates CRS1C-2 by influencing immune signaling, promoting antimicrobial humoral immune responses. This essential trace element supports mucosal immune defenses, providing a potential avenue to fortify the innate immune response against bacterial challenges.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Cholecalciferol activates CRS1C-2 by modulating immune responses, enhancing antimicrobial humoral immune reactions. This fat-soluble vitamin supports mucosal immune defenses, offering potential strategies to amplify the innate immune response against bacterial threats.