CRALBPL inhibitors represent a specialized class of compounds that target the CRALBP-like protein (CRALBPL), which is involved in the intracellular transport and metabolism of retinoids and other lipophilic molecules. These inhibitors are designed to interact specifically with CRALBPL, disrupting its normal function and thereby affecting the dynamics of retinoid signaling pathways. The structural characteristics of CRALBPL inhibitors often include a range of functional groups that allow for selective binding to the protein, modulating its activity through competitive inhibition or alternative binding mechanisms. By precisely tailoring these compounds, researchers can gain insights into the molecular interactions and conformational changes associated with CRALBPL activity.
In laboratory settings, CRALBPL inhibitors are employed to investigate the biochemical and cellular roles of CRALBPL in various biological contexts. By inhibiting the function of this protein, researchers can explore its impact on retinoid signaling, lipid metabolism, and related cellular processes. These studies facilitate a deeper understanding of how CRALBPL contributes to cellular homeostasis and the regulation of metabolic pathways. Additionally, CRALBPL inhibitors serve as useful tools for probing the mechanisms by which cells respond to retinoid signals and for examining the interplay between lipid transport and cellular signaling. The insights gained from these investigations can lead to a more comprehensive understanding of the roles that CRALBPL plays in cellular biology and its potential involvement in broader physiological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
This histone deacetylase inhibitor can alter chromatin structure and potentially downregulate transcription of certain genes, potentially decreasing "clavesin 1" expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, it changes DNA methylation patterns which could lead to the repression of the "clavesin 1" gene. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
By intercalating into DNA, it inhibits transcription elongation and could reduce "clavesin 1" mRNA synthesis. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
This RNA polymerase II inhibitor can prevent mRNA synthesis, potentially reducing "clavesin 1" expression. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
This compound inhibits RNA polymerase II, which may lead to decreased transcription of the "clavesin 1" gene. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that can induce the degradation of transcription factors required for "clavesin 1" expression. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
This eukaryotic translation inhibitor could reduce overall protein synthesis, potentially affecting "clavesin 1" levels. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
As an mTOR inhibitor, it may downregulate protein synthesis pathways, indirectly influencing "clavesin 1" expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
It binds to GC-rich DNA sequences, potentially blocking transcription factors from initiating "clavesin 1" transcription. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
This compound can alkalinize lysosomes and inhibit DNA replication, which might reduce "clavesin 1" expression. | ||||||