CPEB2 Activators
CPEB2 Activators, through their effects on various cellular signaling pathways, indirectly augment the functional activity of CPEB2, a protein pivotal in the regulation of mRNA translation through cytoplasmic polyadenylation. Compounds like Rolipram, Forskolin, IBMX, and Dibutyryl-cAMP modulate cyclic AMP (cAMP) levels, a crucial second messenger in cellular signaling. By elevating cAMP levels, these compounds can enhance CPEB2's activity in mRNA translation regulation. This enhancement likely involves the modulation of signaling pathways that intersect with cytoplasmic polyadenylation, a process central to CPEB2's function. Moreover, (-)-Epigallocatechin Gallate, with its broad effects on cellular signaling, and K-252a, a protein kinase inhibitor, potentially influence CPEB2-mediated mRNA translation regulation. Trichostatin A and 5-Azacytidine, by affecting chromatin remodeling and DNA methylation patterns respectively, may also enhance CPEB2 activity by altering the gene expression landscape in a manner conducive to CPEB2's regulatory role. Brefeldin A, by disrupting the Golgi apparatus, indirectly affects protein synthesis, potentially impacting CPEB2-mediated mRNA translation regulation.
Additionally, compounds like Anisomycin, which inhibits protein synthesis at the translation level, and Rapamycin, an mTOR inhibitor, can have indirect effects on CPEB2's role in the selective translation of mRNAs. Anisomycin's inhibition may lead to feedback mechanisms that enhance CPEB2's selective translation regulation, while Rapamycin's effect on mTOR signaling could influence pathways related to mRNA translation, in which CPEB2 is a key regulator. U0126, as a MEK inhibitor, further contributes to the modulation of mRNA translation regulation pathways, thereby indirectly enhancing CPEB2's activity. Collectively, these CPEB2 Activators, through their multifaceted influences on cellular signaling and gene expression, play a significant role in modulating CPEB2's function in the critical process of mRNA translation regulation, highlighting the intricate network of molecular interactions that govern cellular protein synthesis.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Phosphodiesterase-4 inhibitor, which elevates cAMP levels in neurons, potentially enhancing CPEB2-mediated regulation of mRNA translation by influencing signaling pathways that intersect with cytoplasmic polyadenylation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels and potentially enhancing CPEB2's activity in mRNA translation regulation by modulating signaling pathways that involve cytoplasmic polyadenylation. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
A non-specific inhibitor of phosphodiesterases, increases cAMP and cGMP levels, potentially enhancing CPEB2's role in the regulation of mRNA translation through cytoplasmic polyadenylation. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
A cAMP analog, potentially enhances CPEB2 activity by mimicking the effect of cAMP in regulating mRNA translation through cytoplasmic polyadenylation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Affects various signaling pathways, potentially influencing CPEB2-mediated mRNA translation regulation through its broad effects on cellular signaling. | ||||||
K-252a | 99533-80-9 | sc-200517 sc-200517B sc-200517A | 100 µg 500 µg 1 mg | $129.00 $214.00 $498.00 | 19 | |
An inhibitor of protein kinases, potentially enhances CPEB2 activity by affecting signaling pathways involved in mRNA translation regulation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
An inhibitor of histone deacetylases, potentially influences gene expression patterns in a way that enhances CPEB2-mediated regulation of mRNA translation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, may influence gene expression patterns, potentially enhancing CPEB2 activity in the regulation of mRNA translation. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Disrupts Golgi apparatus function, indirectly affecting protein synthesis and potentially enhancing CPEB2-mediated mRNA translation regulation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, can influence mRNA translation and potentially enhance CPEB2's role in the selective translation of mRNAs. | ||||||