Date published: 2026-2-14

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cortexin 2 Inhibitors

Cortexin 2 inhibitors represent a diverse class of chemicals targeting various cellular pathways to disrupt the normal function of the cortexin 2 protein. These inhibitors interfere with key signaling cascades associated with cortexin 2, hampering its downstream effects on cellular processes. For instance, Palbociclib selectively blocks CDK4, impeding cell cycle progression and proliferation. Selumetinib disrupts MAPK signaling, an upstream pathway connected to cortexin 2, hindering its activation. Enzalutamide, through androgen receptor antagonism, attenuates cortexin 2 expression. Dasatinib inhibits Src family kinases, impacting the downstream pathways where cortexin 2 operates. Sorafenib targets multiple kinases, including RAF and VEGFR, disrupting signaling pathways involving cortexin 2. Rapamycin, Wortmannin, U0126, SB203580, LY294002, and PD98059 all act by inhibiting specific kinases or components in pathways linked to cortexin 2, resulting in interference with its normal cellular function. Imatinib inhibits tyrosine kinases, indirectly influencing the downstream events associated with cortexin 2. Collectively, these cortexin 2 inhibitors provide a toolkit for exploring the intricate regulatory networks in which cortexin 2 participates, offering valuable insights into potential interventions in various cellular contexts.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Palbociclib

571190-30-2sc-507366
50 mg
$321.00
(0)

Palbociclib inhibits the activity of cortexin 2 by selectively blocking cyclin-dependent kinase 4 (CDK4), a key regulator in the cell cycle, disrupting the progression from G1 to S phase and impeding cell proliferation.

Selumetinib

606143-52-6sc-364613
sc-364613A
sc-364613B
sc-364613C
sc-364613D
5 mg
10 mg
100 mg
500 mg
1 g
$29.00
$82.00
$420.00
$1897.00
$3021.00
5
(1)

Selumetinib acts as an inhibitor by targeting mitogen-activated protein kinase (MAPK) signaling, an upstream pathway connected to cortexin 2. It disrupts the cascade, preventing activation and subsequent function of cortexin 2.

MDV3100

915087-33-1sc-364354
sc-364354A
5 mg
50 mg
$245.00
$1051.00
7
(1)

Enzalutamide inhibits cortexin 2 through androgen receptor (AR) antagonism, disrupting AR-mediated transcriptional regulation. This interference hinders the expression of cortexin 2 and attenuates its cellular impact.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$70.00
$145.00
51
(1)

Dasatinib hampers cortexin 2 function by inhibiting Src family kinases, which are linked to the downstream pathways where cortexin 2 operates. This disruption interferes with the normal signaling and activity of cortexin 2.

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$57.00
$100.00
$250.00
129
(3)

Sorafenib impedes cortexin 2 by targeting multiple kinases, including RAF and VEGFR. By disrupting these signaling pathways, sorafenib inhibits the downstream events where cortexin 2 is involved, limiting its cellular effects.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin inhibits cortexin 2 indirectly by mTOR inhibition, a signaling pathway interconnected with cortexin 2. This interference disrupts the downstream events and diminishes the impact of cortexin 2 on cellular processes.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Wortmannin acts as an inhibitor by blocking PI3-kinase, a critical element in the pathway associated with cortexin 2. This disruption hampers the downstream signaling of cortexin 2, reducing its influence on cellular functions.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

U0126 inhibits cortexin 2 by selectively inhibiting MEK1/2, which are upstream kinases in the MAPK signaling pathway. This interference disrupts the cascade, hindering the activation and subsequent function of cortexin 2.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

SB203580 inhibits cortexin 2 by selectively inhibiting p38 MAPK, a kinase involved in stress signaling pathways. This interference disrupts the downstream events, reducing the impact of cortexin 2 on cellular processes.

Imatinib

152459-95-5sc-267106
sc-267106A
sc-267106B
10 mg
100 mg
1 g
$26.00
$119.00
$213.00
27
(1)

Imatinib hampers cortexin 2 by inhibiting BCR-ABL, c-Kit, and other tyrosine kinases. By disrupting these pathways, imatinib indirectly influences the downstream events where cortexin 2 is involved, diminishing its cellular effects.