Date published: 2025-12-24

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Contactin 6 Inhibitors

CNTN6 Inhibitors represents a group of compounds that can inhibit the activity of Contactin 6 (CNTN6), a neural cell adhesion molecule integral to the development and function of the nervous system. The inhibitors in this class are not directly targeted at CNTN6 but rather influence the pathways and processes in which CNTN6 is involved. These compounds are characterized by their diverse mechanisms of action, each impacting a specific aspect of cellular function that relates to the role of CNTN6 in neural development and signaling. By targeting various signaling pathways and cellular processes such as cell adhesion, axon guidance, synaptogenesis, and neuronal migration, these inhibitors can modulate the activity of CNTN6. Their modes of action include altering neuronal activity, disrupting cell surface protein expression, modulating key signaling pathways, and impacting cell growth and proliferation. The design and function of CNTN6 inhibitors are grounded in the understanding that modulating the signaling pathways and cellular processes associated with CNTN6 can influence its activity. These compounds operate by targeting essential cellular mechanisms such as kinase activity, enzyme inhibition, and signal transduction processes. By doing so, they can affect the normal functioning of CNTN6, particularly its role in neural development and cell adhesion. The inhibitors in this class also encompass compounds that interact with intracellular signaling pathways, influencing the downstream effects that contribute to neural development and function. The diversity in the action of these inhibitors reflects the complexity of CNTN6's role in the nervous system, underlining the intricate network of interactions and pathways in which this protein participates. Overall, CNTN6 inhibitors represent a sophisticated and varied class of compounds that play a crucial role in exploring the biological functions of CNTN6. Their ability to modulate key cellular processes and signaling pathways provides important insights into the mechanisms through which CNTN6 operates in the nervous system. The study and application of these inhibitors contribute significantly to the understanding of neural development, cellular communication, and the molecular basis of neural function. As tools for research, CNTN6 inhibitors are invaluable in dissecting the complex role of CNTN6 in neural biology.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Bafilomycin A1

88899-55-2sc-201550
sc-201550A
sc-201550B
sc-201550C
100 µg
1 mg
5 mg
10 mg
$96.00
$250.00
$750.00
$1428.00
280
(6)

Bafilomycin A1 inhibits vacuolar-type H+-ATPase. Disruption in endosomal-lysosomal trafficking could possibly inhibit CNTN6's cell surface expression.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

LY294002 is a PI3K inhibitor. Inhibiting the PI3K pathway, which is crucial in neural development, could possibly inhibit CNTN6 mediated processes.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

PD98059 inhibits MEK in the MAPK/ERK pathway. Disrupting the MAPK/ERK pathway could possibly inhibit CNTN6's function in neural processes.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

SB203580 inhibits p38 MAP kinase, impacting the MAPK pathway. This could possibly inhibit CNTN6's role in neuronal development and response.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin inhibits mTOR, involved in cell growth and proliferation. Inhibiting mTOR could possibly inhibit CNTN6's role in neural development.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin can modulate multiple signaling pathways and might impact neural cell adhesion and growth, potentially inhibiting CNTN6 activity.

Cyclopamine

4449-51-8sc-200929
sc-200929A
1 mg
5 mg
$92.00
$204.00
19
(1)

Cyclopamine inhibits the Hedgehog signaling pathway. Inhibition of this pathway could possibly inhibit CNTN6's function in neural development.

IWP-2

686770-61-6sc-252928
sc-252928A
5 mg
25 mg
$94.00
$286.00
27
(1)

IWP-2 inhibits Wnt processing and secretion. Inhibiting Wnt signaling could possibly inhibit CNTN6's role in neural patterning.

NSC 23766

733767-34-5sc-204823
sc-204823A
10 mg
50 mg
$148.00
$597.00
75
(4)

NSC23766 inhibits Rac1, a small GTPase involved in cytoskeletal rearrangements. Inhibiting Rac1 could possibly inhibit CNTN6's role in cell adhesion and migration.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium Chloride inhibits GSK-3β, potentially impacting Wnt signaling. Inhibition of GSK-3β could possibly inhibit CNTN6 in processes it is involved in.