Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad-spectrum kinase inhibitor that hinders the phosphorylation of COMMD10's substrates, thereby reducing its downstream signaling and functional activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that blocks the PI3K/Akt pathway. Since COMMD10 has a role in this pathway, the inhibition of the pathway leads to decreased COMMD10 activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a MEK1 and MEK2 inhibitor. By inhibiting these kinases, it suppresses the ERK1/2 pathway, which has ties to COMMD10 activity, leading to the reduction of COMMD10′s function. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a selective MEK inhibitor. Its inhibition of MEK suppresses ERK signaling, a pathway in which COMMD10 is involved, leading to a decrease in COMMD10 functional activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor. By inhibiting mTOR, it disrupts the mTOR pathway, which COMMD10 is involved in, leading to decreased COMMD10 activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor. Its inhibition of JNK dampens JNK signaling, a pathway that COMMD10 is involved in, leading to decreased COMMD10 functional activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor. Its action inhibits the p38 MAPK pathway, leading to decreased COMMD10 activity as COMMD10 is involved in this pathway. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent PI3K inhibitor. It inhibits the PI3K/Akt pathway, which COMMD10 is involved in, leading to decreased COMMD10 activity. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $160.00 $345.00 | 12 | |
AZD8055 is a potent mTOR inhibitor. It disrupts the mTOR pathway, which COMMD10 is involved in, leading to decreased COMMD10 activity. | ||||||
GSK 690693 | 937174-76-0 | sc-363280 sc-363280A | 10 mg 50 mg | $255.00 $1071.00 | 4 | |
GSK690693 is an Akt inhibitor. Its inhibition of Akt disrupts the PI3K/Akt pathway, which COMMD10 is involved in, leading to decreased COMMD10 activity. | ||||||