CLP24 inhibitors are a class of chemical compounds that are defined by their unique mechanism of action, which involves the selective interruption of specific biological pathways. The name "CLP24" typically refers to a target within the cell that these inhibitors are designed to interact with. The exact nature of this target can vary depending on the specific biochemical context, but generally, CLP24 is a shorthand notation for a protein, enzyme, receptor, or other molecular structure that plays a critical role in a cellular process. These inhibitors work at the molecular level, binding to their target with high affinity and specificity, which results in the modulation of the activity of the target protein or enzyme.
The development of CLP24 inhibitors requires a deep understanding of the structure and function of the target molecule. This often involves the use of advanced techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, or cryo-electron microscopy to determine the three-dimensional structure of the target. With this information in hand, medicinal chemists can design molecules that fit precisely into the active site or another relevant region of the target, thus blocking its function. The interaction between the CLP24 inhibitor and its target is typically governed by a range of non-covalent forces, such as hydrogen bonds, ionic interactions, van der Waals forces, and hydrophobic effects.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A potent kinase inhibitor that can inhibit protein kinases which might be upstream of CLP24. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that could influence pathways regulating CLP24 activity or stability. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor which can modulate several signaling pathways that may intersect with CLP24. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor that might alter stress-related pathways involving CLP24. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor, which could affect cell survival and proliferation signals linked to CLP24. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor that blocks MEK activation, potentially impacting pathways associated with CLP24. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that could modulate apoptotic pathways involving CLP24. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
Hedgehog signaling pathway inhibitor, could impact pathways influencing CLP24. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor that might prevent the degradation of regulatory proteins affecting CLP24. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Another proteasome inhibitor, could indirectly affect the turnover of CLP24 or its regulators. | ||||||