CLP24 activators represent a distinct category of chemical agents designed to enhance or stimulate the activity of their molecular target, denoted by the CLP24 designation. While the specific identity of CLP24 within the realm of biochemistry is not universally standardized and can refer to various proteins, enzymes, or other critical cellular components, the general principle underlying the function of activators remains consistent. These molecules interact with their target in a manner that leads to an increase in its biological activity, often by inducing a conformational change that results in an upregulation of function or by stabilizing the active form of the target. The mode of action of CLP24 activators is complex and highly specific, as they must selectively bind to their designated target without affecting the activity of other similar molecules within the cellular environment.
The design and synthesis of CLP24 activators are grounded in a comprehensive understanding of the structure and dynamics of the target molecule. This knowledge is typically found in cutting-edge research techniques that allow scientists to elucidate the molecular architecture and functional domains critical for the target's activity. Once the target's structure is known, chemists can tailor small molecules that precisely interact with specific regions of the protein or enzyme, often at allosteric sites that are distinct from the active site. These interactions can lead to an alteration in the spatial configuration of the target, which can enhance its natural activity. The activator compounds are crafted to have an affinity for their target, and their binding is characterized by a variety of intermolecular forces, including but not limited to, hydrogen bonding, electrostatic interactions, and hydrophobic contacts. Selectivity and potency are key focuses in the development of CLP24 activators, as off-target effects can diminish the desired activity enhancement.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid may upregulate CLP24 by binding to retinoic acid receptors that could enhance the transcription of genes including those related to cell adhesion processes. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
As a histone deacetylase inhibitor, Trichostatin A might create a transcription-friendly environment that could upregulate the expression of CLP24 by promoting chromatin relaxation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
By disrupting DNA methylation, 5-Azacytidine could theoretically reactivate silenced genes, potentially including CLP24 if its expression is epigenetically regulated. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin might stimulate CLP24 expression through cAMP-dependent pathways, which could influence genes implicated in cell permeability and adhesion. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate might increase CLP24 expression by inhibiting histone deacetylases, leading to a state of hyperacetylation that typically stimulates gene expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin Gallate might induce the expression of CLP24 through its role in activating pathways that respond to oxidative stress, a process potentially relevant to cellular permeability. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol could potentially stimulate CLP24 expression by activating sirtuin pathways, which may influence the transcription of various genes, including those involved in cellular junctions. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone might upregulate CLP24 expression by interacting with glucocorticoid receptors, which can bind to glucocorticoid response elements in the promoters of target genes. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
LPS could hypothetically upregulate CLP24 expression as part of its role in initiating immune responses, which might influence genes related to cell barrier functions. | ||||||